1,2,3-噻唑(1,5-a)吡啶合成路线 （共 26 条）
反应条件
[bis(acetoxy)iodo]benzene in dichloromethane T=20°C; Cyclization; 0.5 h;
参考文献
Prakash, Om; Gujral, Harpreet K.; Rani, Neena; Singh, Shiv P.
Synthetic Communications, 2000 , vol. 30, # 3 p. 417 - 425
反应条件
1: With polystyrene-sulfonyl hydrazide resin; titanium tetrachloride in methanol; dichloromethane T=20°C; 12 h; 2: With morpholine T=95°C; 4 h; Further stages.;
参考文献
Raghavendra, Makam S.; Lam, Yulin
Tetrahedron Letters, 2004 , vol. 45, # 32 p. 6129 - 6132
反应条件
water; sodium hydroxide in ethanol
参考文献
Abarca, Belen; Adam, Rosa; Ballesteros, Rafael
Arkivoc, 2010 , vol. 2010, # 3 p. 319 - 327
参考文献
Liu, Sheng; Sawicki, James; Driver, Tom G.
Organic Letters, 2012 , vol. 14, # 14 p. 3744 - 3747
反应条件
n-butyllithium; 1,1-dibromo-tetrachloro-ethane 1.) -40 deg C, 2.5 h, toluene; 2.) from -40 deg C to room temp., toluene; Yield given. Multistep reaction;
参考文献
Abarca, Belen; Ballesteros, Rafael; Mojarred, Fatemeh; Jones, Gurnos; Mouat, Deborah J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 1865 - 1868
反应条件
1: iodine; potassium hydroxide / dimethylformamide 2: aq. sodium carbonate; Pd(PPh3)4 / dioxane / 85 °C View Scheme
参考文献
Abarca, Belen; Aucejo, Ricardo; Ballesteros, Rafael; Blanco, Fernando; Garcia-Espana, Enrique
Tetrahedron Letters, 2006 , vol. 47, # 46 p. 8101 - 8103
反应条件
1: iodine; potassium hydroxide / dimethylformamide 2: 54 percent / aq. sodium carbonate; Pd(PPh3)4 / dioxane / 24 h / 85 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 47, # 46 p. 8101 - 8103
反应条件
palladium diacetate; caesium carbonate; triphenylphosphine T=140°C; Inert atmosphere;
参考文献
Arkivoc, , vol. 2012, # 9 p. 229 - 241
反应条件
palladium diacetate; caesium carbonate; triphenylphosphine in N,N-dimethyl-formamide T=160°C; 24 h; Inert atmosphere;
参考文献
Arkivoc, , vol. 2012, # 9 p. 229 - 241
反应条件
PCy3*HBF4; palladium diacetate; potassium carbonate; 2,2,2-trimethylacetic acid in dimethyl amine T=100°C; 72 h; Inert atmosphere;
参考文献
Abarca, Belen; Adam, Rosa; Ballesteros, Rafael; Chiassai, Leonardo; Gamon, Cristina
Arkivoc, 2012 , vol. 2012, # 9 p. 229 - 241
