吡唑并[1,5-a]吡啶合成路线 （共 14 条）
反应条件
acetic acid in dichloromethane Mannich reaction;
参考文献
Prante; Loeber; Huebner; Gmeiner; Kuwert
Journal of Labelled Compounds and Radiopharmaceuticals, 2001 , vol. 44, # 12 p. 849 - 858
反应条件
trichlorophosphate 1 h; Ambient temperature;
参考文献
Tanji, Ken-ichi; Sasahara, Takehiko; Suzuki, Junko; Higashino, Takeo
Heterocycles, 1993 , vol. 35, # 2 p. 915 - 924
反应条件
1: With n-butyllithium in tetrahydrofuran; hexane T=-78°C; Metallation; 0.5 h; 2: With 1,2-di-iodoethane in tetrahydrofuran; hexane T=-78°C; Iodination; 3 h;
参考文献
Aboul-Fadl; Lober; Gmeiner
Synthesis, 2000 , # 12 p. 1727 - 1732
反应条件
1: N-iodo-succinimide / acetonitrile / 1 h / 20 °C 2: isopropylmagnesium chloride lithium chloride complex / tetrahydrofuran / 2 h / 5 - 10 °C / Inert atmosphere View Scheme
参考文献
Bethel, Paul A.; Campbell, Andrew D.; Goldberg, Frederick W.; Kemmitt, Paul D.; Lamont, Gillian M.; Suleman, Abid
Tetrahedron, 2012 , vol. 68, # 27-28 p. 5434 - 5444
