(3aR,6R,6aR)-6-(羟基甲基)螺[6,6a-二氢-3aH-呋喃并[4,3-d][1,3]二氧杂环戊烯-2,1'-环己烷]-4-酮合成路线 （共 9 条）
反应条件
boron trifluoride diethyl etherate in tetrahydrofuran 7 h; Ambient temperature;
参考文献
Miller, Scott A.; Chamberlin, A. Richard
Journal of the American Chemical Society, 1990 , vol. 112, # 22 p. 8100 - 8112
反应条件
Sikkon; iron(III) chloride T=50°C; 2.5 h;
参考文献
Beer; Meuwly; Vasella
Helvetica Chimica Acta, 1982 , vol. 65, # 8 p. 2570 - 2582
反应条件
pyridinium chlorochromate in dichloromethane 16 h; Ambient temperatureor with pyridinium dichromate;
参考文献
Liu; Caperelli
Synthesis, 1991 , # 11 p. 933 - 934
反应条件
(1S)-10-camphorsulfonic acid in xylene 13 h; Heating;
参考文献
Takano, Seiichi; Inomata, Kohei; Ogasawara, Kunio
Heterocycles, 1988 , vol. 27, # 10 p. 2413 - 2416
反应条件
1: 82 percent / conc. H2SO4 / 2 h / Ambient temperature 2: 59 percent / pyridinium chlorochromate / CH2Cl2 / 16 h / Ambient temperature; or with pyridinium dichromate View Scheme
参考文献
Liu; Caperelli
Synthesis, 1991 , # 11 p. 933 - 934
反应条件
1: 82 percent / conc. H2SO4 / 2 h / Ambient temperature 2: 59 percent / pyridinium chlorochromate / CH2Cl2 / 16 h / Ambient temperature; or with pyridinium dichromate View Scheme
参考文献
Liu; Caperelli
Synthesis, 1991 , # 11 p. 933 - 934
反应条件
1: 1.) aq. KOH, 2.) aq. KIO4 / 1.) 40 deg C, 15 min, 2.) 4 deg C, 5 h 2: pyridinium p-toluenesulfonate / 12 h / 60 °C View Scheme
参考文献
Marien; Esmans; Lemiere; Dommisse
Synthetic Communications, 1997 , vol. 27, # 2 p. 205 - 224
反应条件
sodium hydroxide; sodium periodate in 1,4-dioxane T=0°C; 0.166667 h;
参考文献
Liu; Caperelli
Synthesis, 1991 , # 11 p. 933 - 934
反应条件
1: 1.) aq. KOH, 2.) aq. KIO4 / 1.) 40 deg C, 15 min, 2.) 4 deg C, 5 h
2: pyridinium p-toluenesulfonate / 12 h / 60 °C
3: 1.) BuLi / 1.) THF, hexane, -78 deg C, 15 min, 2.) THF, hexane, -78 deg C (3 h), -> room temp. (1 h)
View Scheme
参考文献
Marien; Esmans; Lemiere; Dommisse
Synthetic Communications, 1997 , vol. 27, # 2 p. 205 - 224
