Dess-Martin periodane in dichloromethane Inert atmosphere;

1: With tert.-butylhydroperoxide; selenium(IV) oxide in dichloromethane T=20°C; 9 h; 2: With triphenylphosphine in dichloromethane T=0°C; 12 h;

1: 98 percent / NaN3 / dimethylsulfoxide / 0.2 h / microwave irradiation 2: 95 percent / Ph3P / dimethylsulfoxide / 0.25 h / microwave irradiation 3: aq. HCl / CH2Cl2 / 24 h View Scheme

1: Streptomyces clavuligerus L-lysine ε-aminotransferase / aq. phosphate buffer / 1 h / 37 °C / pH 7.2 2: aq. phosphate buffer / 2 h / 20 °C / pH 7.2 View Scheme

1.1: EtBr; TMEDA / tetrahydrofuran / 12 h / -78 °C 2.1: 14.7 g / TFA / CH2Cl2 / 24 h / 20 °C 3.1: TBHP; SeO2 / CH2Cl2 / 9 h / 20 °C 3.2: 25 percent / PPh3 / CH2Cl2 / 12 h / 0 °C View Scheme

1: 49 percent / pyridinium chlorochromate / CH2Cl2 / 2.5 h / Ambient temperature 2: 21 percent / 3-benzyl-5-(2-hydroxyethyl)-4-methylthiazolium chloride, Et3N / 1.5 h / 80 °C 3: TFA / CH2Cl2 / 3 h / Ambient temperature 4: 35 percent / phosphate buffer pH 9.0 / 0.5 h / 100 °C / var. pH View Scheme

1: 21 percent / 3-benzyl-5-(2-hydroxyethyl)-4-methylthiazolium chloride, Et3N / 1.5 h / 80 °C 2: TFA / CH2Cl2 / 3 h / Ambient temperature 3: 35 percent / phosphate buffer pH 9.0 / 0.5 h / 100 °C / var. pH View Scheme

1: 75 percent / Et3N / dioxane; H2O / 2 h / Ambient temperature 2: 49 percent / pyridinium chlorochromate / CH2Cl2 / 2.5 h / Ambient temperature 3: 21 percent / 3-benzyl-5-(2-hydroxyethyl)-4-methylthiazolium chloride, Et3N / 1.5 h / 80 °C 4: TFA / CH2Cl2 / 3 h / Ambient temperature 5: 35 percent / phosphate buffer pH 9.0 / 0.5 h / 100 °C / var. pH View Scheme

1: TFA / CH2Cl2 / 3 h / Ambient temperature 2: 35 percent / phosphate buffer pH 9.0 / 0.5 h / 100 °C / var. pH View Scheme

hydrogenchloride in dichloromethane 24 h;