(S)-1-(4-甲基苯基)乙胺合成路线 （共 18 条）
反应条件
Novozym 435 T=23°C; 3 h; Molecular sieveEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Ditrich, Klaus
Synthesis, 2008 , # 14 SPEC. ISS. art. no. C01108SS, p. 2283 - 2287
反应条件
1: With [((R)-tol-binap)RuCl2(DMF)x]; ammonia; ammonium formate in methanol T=85°C; Leuckart-Wallach reaction; 21 h; 2: With hydrogenchloride in ethanol 1 h; Heating; Title compound not separated from byproducts;
参考文献
Xie, Ying; Pan, Hongjie; Xiao, Xiao; Li, Songlei; Shi, Yian
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 45 p. 8960 - 8962,3
Title/Abstract Full Text Show Details
Xie, Ying; Pan, Hongjie; Xiao, Xiao; Li, Songlei; Shi, Yian
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 45 p. 8960 - 8962
反应条件
6-(1,2:3,4-di-O-isopropylidene-α-D-galactopyranosyl) hydrogen phthalate in isopropyl alcohol Heating;
参考文献
Mereyala, Hari Babu; Fatima, Liyakat; Pola, Pallavi
Tetrahedron Asymmetry, 2004 , vol. 15, # 4 p. 585 - 587
反应条件
hexacarbonyl molybdenum in water; acetonitrile T=85°C; 1 h;
参考文献
Atobe, Masakazu; Yamazaki, Naoki; Kibayashi, Chihiro
Journal of Organic Chemistry, 2004 , vol. 69, # 17 p. 5595 - 5607
反应条件
Candida antarctica lipase B; hydrogen; nickel in toluene T=70°C; P=75.0075 Torr; 72 h; AutoclaveEnzymatic reaction; optical yield given as percent ee;
参考文献
Parvulescu, Andrei N.; Jacobs, Pierre A.; De Vos, Dirk E.
Advanced Synthesis and Catalysis, 2008 , vol. 350, # 1 p. 113 - 121
反应条件
sodium tetrahydroborate; borane; enantiopure spiroborate ester in 1,4-dioxane 36 h;
参考文献
Huang, Xiaogen; Ortiz-Marciales, Margarita; Huang, Kun; Stepanenko, Viatcheslav; Merced, Francisco G.; Ayala, Angel M.; Correa, Wildeliz; De Jesus, Melvin
Organic Letters, 2007 , vol. 9, # 9 p. 1793 - 1795
反应条件
1: NaH / dimethylformamide / 20 °C 2: borane; NaBH4 / enantiopure spiroborate ester / dioxane / 36 h View Scheme
参考文献
Huang, Xiaogen; Ortiz-Marciales, Margarita; Huang, Kun; Stepanenko, Viatcheslav; Merced, Francisco G.; Ayala, Angel M.; Correa, Wildeliz; De Jesus, Melvin
Organic Letters, 2007 , vol. 9, # 9 p. 1793 - 1795
反应条件
formate dehydrogenase; Arthrobacter citreus S9 ω-transaminase; ATA-113 ω-transaminase; sodium formate; isopropylamine; Reduced nicotinamide-adenine dinucleotide; yeast alcohol dehydrogenase pH=7; aq. phosphate bufferEnzymatic reaction; optical yield given as percent ee;
参考文献
Cassimjee, Karim Engelmark; Branneby, Cecilia; Abedi, Vahak; Wells, Andrew; Berglund, Per
Chemical Communications, 2010 , vol. 46, # 30 p. 5569 - 5571
反应条件
D-(+)-camphoric acid
参考文献
Kinbara, Kazushi; Sakai, Kenichi; Hashimoto, Yukihiko; Nohira, Hiroyuki; Saigo, Kazuhiko
Tetrahedron Asymmetry, 1996 , vol. 7, # 6 p. 1539 - 1542
Title/Abstract Full Text View citing articles Show Details
Pallavicini, Marco; Valoti, Ermanno; Villa, Luigi; Piccolo, Oreste
Tetrahedron Asymmetry, 1997 , vol. 8, # 7 p. 1069 - 1073
反应条件
1: With (Ph)2SiH2; silver trifluoromethanesulfonate in ethylene glycol dimethyl ether T=20°C; 40 h; 2: With hydrogenchloride in methanol; ethylene glycol dimethyl ether Further stages. Title compound not separated from byproducts.;
参考文献
Takei; Nishibayashi; Ishii; Mizobe; Uemura; Hidai
Chemical Communications, 2001 , # 22 p. 2360 - 2361
