2-巯基-5-甲基苯并咪唑合成路线 （共 29 条）
反应条件
carbon disulfide; sodium hydroxide in hydrogenchloride; ethanol
参考文献
G. D. Searle and Co.
Patent: US4687775 A1, 1987 ;
反应条件
sodium hydroxide in ethanol; water 3 h; Heating;
参考文献
Eisai Co., Ltd.
Patent: US2007/10542 A1, 2007 ;
Location in patent: Page/Page column 71-72 ;
反应条件
tributoxyborane; butan-1-ol in toluene T=108°C; 22 h; Heating / reflux;
参考文献
Kuraray Co., Ltd.
Patent: US6350876 B2, 2002 ;
Location in patent: Example 20 ;
反应条件
1: H2 / 5percent Pd/C 2: 21.3 percent / dimethylformamide / 120 h / Ambient temperature View Scheme
参考文献
Tanaka, Kenjiro; Shimazaki, Michiko; Murakami, Yasuoki
Chemical & Pharmaceutical Bulletin, 1982 , vol. 30, # 8 p. 2714 - 2722
反应条件
in ethanol; water 8 h; Heating;
参考文献
Uchida; Morita; Chihiro; Kanbe; Yamasaki; Yabuuchi; Nakagawa
Chemical and Pharmaceutical Bulletin, 1989 , vol. 37, # 6 p. 1517 - 1523
反应条件
in N,N-dimethyl-formamide 0.0666667 h; Microwave irradiation; TemperatureTime;
参考文献
Mahesh Kumar; Dubey
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2012 , vol. 51, # 11 p. 1619 - 1622
反应条件
in N,N-dimethyl-formamide 120 h; Ambient temperature;
参考文献
Tanaka, Kenjiro; Shimazaki, Michiko; Murakami, Yasuoki
Chemical & Pharmaceutical Bulletin, 1982 , vol. 30, # 8 p. 2714 - 2722
反应条件
sodium hydroxide in ethanol
参考文献
Mavrova, Anelia Ts.; Vuchev, Dimitar; Anichina, Kameliya; Vassilev, Nikolay
European Journal of Medicinal Chemistry, 2010 , vol. 45, # 12 p. 5856 - 5861
反应条件
Microwave irradiation;
参考文献
Mahesh Kumar; Dubey
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2012 , vol. 51, # 11 p. 1619 - 1622
反应条件
DBN in N,N-dimethyl-formamide T=45 - 55°C; 14 h;
参考文献
Lazer; Matteo; Possanza
Journal of Medicinal Chemistry, 1987 , vol. 30, # 4 p. 726 - 729
