呋喃并[3,2-b]吡啶合成路线 （共 41 条）
反应条件
copper(l) iodide; triethylamine; trimethylsilylacetylene; bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran T=20°C; 1 h;
参考文献
ARRAY BIOPHARMA INC.
Patent: WO2005/51304 A2, 2005 ;
Location in patent: Page/Page column 144 ;
WO 2005/051304 A2
反应条件
sodium carbonate; tetrakis(triphenylphosphine) palladium(0) in water; N,N-dimethyl-formamide T=120°C; 2 h; Microwave irradiation;
参考文献
NOVARTIS AG; BETSCHART, Claudia; COTESTA, Simona; HINTERMANN, Samuel; WAGNER, Juergen; ROY, Bernard, Lucien; GERSPACHER, Marc; VON MATT, Anette; BEHNKE, Dirk
Patent: WO2011/73316 A1, 2011 ;
Location in patent: Page/Page column 69-70 ;
WO 2011/073316 A1
反应条件
phosphoric acid T=170 - 180°C; 15 h;
参考文献
Shiotani, Shunsaku; Morita, Hiroyuki
Journal of Heterocyclic Chemistry, 1986 , vol. 23, # 3 p. 665 - 668
反应条件
potassium fluoride in methanol T=20°C;
参考文献
Chartoire, Anthony; Comoy, Corinne; Fort, Yves
Tetrahedron, 2008 , vol. 64, # 48 p. 10867 - 10873
反应条件
T=650°C; P=0.01 Torr; 3 h;
参考文献
Hickson, Clare L.; McNab, Hamish
Synthesis, 1981 , # 6 p. 464 - 465
反应条件
sodium carbonate; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran; water; toluene Suzuki coupling; 18 h; Heating;
参考文献
Chartoire, Anthony; Comoy, Corinne; Fort, Yves
Tetrahedron, 2008 , vol. 64, # 48 p. 10867 - 10873
反应条件
trichlorophosphate in chloroform 7 h;
参考文献
Shiotani, Shunsaku; Kurosaki, Masahide; Taniguchi, Katsunori; Moriyama, Miwa
Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 3 p. 941 - 952
反应条件
1: 88 percent / m-chloroperbenzoic acid / CHCl3 / 18 h / Ambient temperature 2: 9 percent / 1 h / 90 °C View Scheme
参考文献
Shiotani, Shunsaku; Kurosaki, Masahide; Taniguchi, Katsunori; Moriyama, Miwa
Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 3 p. 941 - 952
反应条件
trimethylsilyl cyanide; triethylamine in acetonitrile 20 h; Heating;
参考文献
Shiotani, Shunsaku; Kurosaki, Masahide; Taniguchi, Katsunori; Moriyama, Miwa
Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 3 p. 941 - 952
反应条件
1: 90 percent / KOH / ethanol / 0.25 h / Heating 2: 21 percent / 3 h / 650 °C / 0.01 Torr View Scheme
参考文献
Hickson, Clare L.; McNab, Hamish
Synthesis, 1981 , # 6 p. 464 - 465
