5H-吡咯[3,2-D]嘧啶合成路线 （共 5 条）
反应条件
hydrogen; sodium hydrogencarbonate; palladium 10 on activated carbon in ethanol T=20°C; 3 h;
参考文献
CYTOPIA RESEARCH PTY LTD
Patent: WO2009/62258 A1, 2009 ;
Location in patent: Page/Page column 99 ;
WO 2009/062258 A1
反应条件
ammonium hydroxide; hydrogen; palladium dichloride in ethanol Ambient temperature;
参考文献
Ektova, L. V.; Preobrazhenskaya, M. N.
Pharmaceutical Chemistry Journal, 1988 , vol. 22, # 7 p. 572 - 574
Khimiko-Farmatsevticheskii Zhurnal, 1988 , vol. 22, # 7 p. 860 - 863
反应条件
tin in dichloromethane; acetic acid T=20°C; Diels-Alder Cycloaddition; 2 h; Inert atmosphere; ConcentrationTemperatureTime;
参考文献
De Rosa, Michael; Arnold, David; Hartline, Douglas
Journal of Organic Chemistry, 2013 , vol. 78, # 17 p. 8614 - 8623
反应条件
1: 70 percent / POCl3 / ethanol / 4 h / Heating 2: 79 percent / H2, aq. 25percent NH3 / PdCl2 / ethanol / Ambient temperature View Scheme
参考文献
Ektova, L. V.; Preobrazhenskaya, M. N.
Pharmaceutical Chemistry Journal, 1988 , vol. 22, # 7 p. 572 - 574
Khimiko-Farmatsevticheskii Zhurnal, 1988 , vol. 22, # 7 p. 860 - 863
反应条件
in dichloromethane; acetic acid T=20°C; Diels-Alder Cycloaddition; 4 h; Inert atmosphere; ConcentrationTime;
参考文献
De Rosa, Michael; Arnold, David; Hartline, Douglas
Journal of Organic Chemistry, 2013 , vol. 78, # 17 p. 8614 - 8623
