3-氧基四氢噻吩-2-羧酸甲酯合成路线

参考文献

MENARINI INTERNATIONAL OPERATIONS LUXEMBOURG S.A.
Patent: WO2006/97449 A1, 2006 ;
Location in patent: Page/Page column 24-25 ;

7400-45-53-[(2-甲氧基-2-乙氧基)硫醇]甲基丙酸

2689-69-23-氧基四氢噻吩-2-羧酸甲酯

参考文献

CELLZOME LIMITED; LYNCH, Rosemary; CANSFIELD, Andrew David; HARDY, Daniel Paul; FEUTRILL, John Thomas; ADREGO, Rita; ELLARD, Katie; LADDUWAHETTY, Tammy
Patent: WO2013/50508 A1, 2013 ;
Location in patent: Page/Page column 44; 62 ;

7400-45-53-[(2-甲氧基-2-乙氧基)硫醇]甲基丙酸

2689-69-23-氧基四氢噻吩-2-羧酸甲酯

参考文献

BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH and CO. KG
Patent: WO2009/52138 A1, 2009 ;
Location in patent: Page/Page column 65-66 ;

78647-28-6

2689-69-23-氧基四氢噻吩-2-羧酸甲酯

参考文献

Yamada, Yasuji; Ishii, Toshihide; Kimura, Masayuki; Hosaka, Kunio
Tetrahedron Letters, 1981 , vol. 22, # 14 p. 1353 - 1354

5331-07-7

2689-69-23-氧基四氢噻吩-2-羧酸甲酯

参考文献

Moore; Moore
Journal of the American Chemical Society, 1946 , vol. 68, p. 910
Chem.Abstr., 1945 , p. 1164

2365-48-2巯基乙酸甲酯+

292638-85-8丙烯酸甲酯

2689-69-23-氧基四氢噻吩-2-羧酸甲酯

参考文献

Jones, John O.; McElhinney, R. Stanley
Journal of Chemical Research, Miniprint, 1984 , # 5 p. 1501 - 1517

2365-48-2巯基乙酸甲酯+

292638-85-8丙烯酸甲酯

2689-69-23-氧基四氢噻吩-2-羧酸甲酯+

2689-68-14-氧四氢噻酚-3-羧酸甲酯

参考文献

Liu, Hsing-Jang; Ngooi, Teng Ko
Canadian Journal of Chemistry, 1982 , vol. 60, p. 437 - 439

2689-69-23-氧基四氢噻吩-2-羧酸甲酯

42558-50-9(S)-羟基戊酸甲酯

参考文献

Hoffmann, Reinhard W.; Helbig, Wilfried; Ladner, Wolfgang
Tetrahedron Letters, 1982 , vol. 23, # 34 p. 3479 - 3482

2689-69-23-氧基四氢噻吩-2-羧酸甲酯

42558-50-9(S)-羟基戊酸甲酯

参考文献

Hoffmann, Reinhard W.; Helbig, Wilfried; Ladner, Wolfgang
Tetrahedron Letters, 1982 , vol. 23, # 34 p. 3479 - 3482

2689-69-23-氧基四氢噻吩-2-羧酸甲酯

913581-92-76,7-二氢噻吩并[3,2-d]嘧啶-2,4-二醇

参考文献

BOEHRINGER INGELHEIM INTERNATIONAL GMBH; POUZET, Pascale, A., J.; NICKOLAUS, Peter; WERTHMANN, Ulrike; FRUTOS, Rogelio, P.; YANG, Bing-Shiou; KIM, Soojin; MULDER, Jason, Alan; PATEL, Nitinchandra; SENANAYAKE, Chris, H.; TAMPONE, Thomas, G.; WEI, Xudong
Patent: WO2013/26797 A1, 2013 ;