2,6-二氯嘧啶-4-羰酰氯合成路线 （共 4 条）
反应条件
trichlorophosphate in N,N-dimethyl-formamide T=110°C;
参考文献
PURDUE PHARMA L.P.; SHAO, Bin
Patent: WO2013/72758 A1, 2013 ;
Location in patent: Page/Page column 93 ;
反应条件
1: hydrogenchloride / N,N-dimethyl-formamide / 2 h / 70 °C 2: phosphorus pentachloride; trichlorophosphate / 3 h / 20 °C / Reflux View Scheme
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH
Patent: US2011/59954 A1, 2011 ;
US 20110059954 A1
反应条件
in water T=20°C; Gershon's procedure; 10 h;
参考文献
Journal of the American Chemical Society, , vol. 122, # 21 p. 5017 - 5024
反应条件
in water
T=20°C; Gershon's procedure; 10 h;
参考文献
Xie, Chaoyu; Runnegar, Maria T. C.; Snider, Barry B.
Journal of the American Chemical Society, 2000 , vol. 122, # 21 p. 5017 - 5024
