2-氯-N,N-二甲基乙酰胺合成路线 （共 38 条）
反应条件
sodium hydroxide in 1,2-dichloro-ethane T=-5°C; 0.5 h;
参考文献
Miyazawa, Toshifumi; Tanaka, Kayoko; Ensatsu, Eiichi; Yanagihara, Ryoji; Yamada, Takashi
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 1 p. 87 - 93
反应条件
sodium hydroxide in dichloromethane 0.25 h;
参考文献
Kem, Kenneth M.; Nguyen, Nghi V.; Cross, Dennis J.
Journal of Organic Chemistry, 1981 , vol. 46, p. 5188 - 5192
反应条件
in tetrahydrofuran; dichloromethane T=-40°C; 1 h;
参考文献
Haley, Gregory Jay; Kong, Norman; Liu, Emily Aijun; Simonsen, Klaus B.; Vu, Binh Thanh; Webber, Stephen Evan
Patent: US2004/259884 A1, 2004 ;
Location in patent: Page 15 ;
反应条件
diethyl ether T=-60°C;
参考文献
Coleman; Peterson; Goheen
Journal of the American Chemical Society, 1936 , vol. 58, p. 1876
参考文献
Boehringer Mannheim GmbH
Patent: US6121322 A1, 2000 ;
US 6121322 A
反应条件
1: chloroacetic acid With dicyclohexyl-carbodiimide in dichloromethane T=20°C; 0.5 h; 2: dimethyl amine With 4-(N,N-dimethlyamino)pyridine in dichloromethane T=20°C;
参考文献
Falco, Jose Luis; Pique, Maria; Gonzalez, Miguel; Buira, Irma; Mendez, Eva; Terencio, Jose; Perez, Cristina; Princep, Marta; Palomer, Albert; Guglietta, Antonio
European Journal of Medicinal Chemistry, 2006 , vol. 41, # 8 p. 985 - 990
参考文献
Boehme,H.; Backhaus,P.
Justus Liebigs Annalen der Chemie, 1975 , p. 1790 - 1796
反应条件
chloroacetyl chloride Heating;
参考文献
Nuretdinova, O. N.; Guseva, F. F.; Troitskaya, L. B.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1991 , vol. 40, # 12 p. 2493 - 2495
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1991 , vol. 40, # 12 p. 2858 - 2860
参考文献
Coleman; Peterson; Goheen
Journal of the American Chemical Society, 1936 , vol. 58, p. 1876
参考文献
Farbenfabr.Bayer
Patent: DE875807 , 1951 ;
