5,6-亚甲基二氧基吲哚合成路线 （共 23 条）
反应条件
silica gel; iron in cyclohexane; acetic acid; benzene 1 h; Heating;
参考文献
Sinhababu; Borchardt
Journal of Organic Chemistry, 1983 , vol. 48, # 19 p. 3347 - 3349
反应条件
N1-(2-Amino-ethyl)-ethane-1,2-diamine in methanol T=30°C; 20 h;
参考文献
Lutz; McNamara; Olinger; et al.
Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 4 p. 1183 - 1188
反应条件
sodium dithionite; sodium acetate in water 48 h;
参考文献
Lutz; McNamara; Olinger; et al.
Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 4 p. 1183 - 1188
参考文献
Hoffmann-La Roche Inc.
Patent: US3976639 A1, 1976 ;
反应条件
copper diacetate; palladium diacetate; potassium carbonate in toluene 24 h; Inert atmosphereReflux;
参考文献
Harada, Rika; Nishida, Naoto; Uchiito, Shiho; Onozaki, Yu; Kurono, Nobuhito; Senboku, Hisanori; Masao, Tokuda; Ohkuma, Takeshi; Orito, Kazuhiko
European Journal of Organic Chemistry, 2012 , # 2 p. 366 - 379
反应条件
1: SnCl2, HCl 2: 83 percent / pyridine / diethyl ether / 1 h / 0 °C 3: 1.) ozonized air, 2.) dimethyl sulfide / 1.) methanol, -78 deg C, 2.) room temperatuer, 40 min; 4: 86 percent / diethylenetriamine / methanol / 20 h / 30 °C View Scheme
参考文献
Lutz; McNamara; Olinger; et al.
Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 4 p. 1183 - 1188
反应条件
1: bromine / acetic acid 2: copper diacetate; palladium diacetate; potassium carbonate / toluene / 24 h / Inert atmosphere; Reflux View Scheme
参考文献
Harada, Rika; Nishida, Naoto; Uchiito, Shiho; Onozaki, Yu; Kurono, Nobuhito; Senboku, Hisanori; Masao, Tokuda; Ohkuma, Takeshi; Orito, Kazuhiko
European Journal of Organic Chemistry, 2012 , # 2 p. 366 - 379
反应条件
1: ammonium acetate; acetic acid / Heating 2: FeCl3·6H2O; carbon; hydrazine hydrate / isopropyl alcohol / 5 h / 80 °C View Scheme
参考文献
Lee, Geunsoo; Choi, Jaehwan; Lee, Byung Min; Kim, Byeong Hyo
Heterocycles, 2013 , vol. 87, # 1 p. 155 - 162
反应条件
1: 83 percent / pyridine / diethyl ether / 1 h / 0 °C 2: 1.) ozonized air, 2.) dimethyl sulfide / 1.) methanol, -78 deg C, 2.) room temperatuer, 40 min; 3: 86 percent / diethylenetriamine / methanol / 20 h / 30 °C View Scheme
参考文献
Lutz; McNamara; Olinger; et al.
Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 4 p. 1183 - 1188
反应条件
1: 1.) ozonized air, 2.) dimethyl sulfide / 1.) methanol, -78 deg C, 2.) room temperatuer, 40 min; 2: 86 percent / diethylenetriamine / methanol / 20 h / 30 °C View Scheme
参考文献
Lutz; McNamara; Olinger; et al.
Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 4 p. 1183 - 1188
