7-氯-3,4-二氢-2H-1-萘酮合成路线 （共 23 条）
反应条件
Diazotization.Behandeln mit Kupfer(I)-chlorid;
参考文献
AstraZeneca AB
Patent: US6265397 B1, 2001 ;
US 6265397 B1
反应条件
polyphosphoric acid T=90°C; 0.166667 h;
参考文献
Carroll, F. Ivy; Blough, Bruce E.; Abraham, Philip; Mills, Andrew C.; Holleman, J. Ashley; Wolckenhauer, Scott A.; Decker, Ann M.; Landavazo, Antonio; McElroy, K. Timothy; Navarro, Hernan A.; Gatch, Michael B.; Forster, Michael J.
Journal of Medicinal Chemistry, 2009 , vol. 52, # 21 p. 6768 - 6781
参考文献
Zeneca Limited
Patent: US5502048 A1, 1996 ;
US 5502048 A
反应条件
PPA in (2S)-N-methyl-1-phenylpropan-2-amine hydrate
参考文献
E. R. Squibb and Sons, Inc.
Patent: US3985731 A1, 1976 ;
反应条件
sulfuric acid; chlorine; silver sulphate in tetrachloromethane; water 2 h;
参考文献
Chen; Gilman
Journal of Heterocyclic Chemistry, 1983 , vol. 20, # 3 p. 663 - 666
反应条件
(i) N2H4, KOH, HOCH2CH2OH, (ii) polyphosphoric acid; Multistep reaction;
参考文献
Crosby, Ian T.; Shin, James K.; Capuano, Ben
Australian Journal of Chemistry, 2010 , vol. 63, # 2 p. 211 - 226
反应条件
aluminium trichloride in carbon disulfide 3 h; Heating; Yield given;
参考文献
Inoue, Kenichiro; Ueda, Shinichi; Nayeshiro, Hidekazu; Moritome, Nobuharu; Inouye, Hiroyuki
Phytochemistry (Elsevier), 1984 , vol. 23, # 2 p. 313 - 318
反应条件
aluminium trichloride T=0 - 100°C; Fiedel-Crafts acylation; 3 h;
参考文献
Caldwell, John P.; Matasi, Julius J.; Zhang, Hongtao; Fawzi, Ahmad; Tulshian, Deen B.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 8 p. 2281 - 2284
反应条件
2: 80 percent / PPA View Scheme
参考文献
Owton; Brunavs
Synthetic Communications, 1991 , vol. 21, # 8-9 p. 981 - 987
参考文献
Schroeter et al.
Chemische Berichte, 1930 , vol. 63, p. 1308,1325
