(E)-3-甲酰基丁-2-烯基乙酸酯合成路线 （共 13 条）
反应条件
1: 90 percent / ammoniumnitrate / ethanol / 15 h 2: KOH / H2O; ethanol / 19.5 h / Ambient temperature View Scheme
参考文献
Bestmann, Hans Juergen; Ermann, Peter; Rueppel, Hartmann; Sperling, Walter
Liebigs Annalen der Chemie, 1986 , # 3 p. 479 - 498
反应条件
dimethyl sulfoxide in tetrahydrofuran; hexane; water
参考文献
Takeda Chemical Industries, Ltd.
Patent: US5424478 A1, 1995 ;
反应条件
sodium chloride; potassium tert-butylate in tetrahydrofuran; water; N,N-dimethyl-formamide; Petroleum ether
参考文献
Shen, Runpu; Pi, Shiqing; Xie, Bin; Huang, Hongjun
Patent: US2002/151742 A1, 2002 ;
反应条件
sodium t-butanolate in water; N,N-dimethyl-formamide; toluene
参考文献
Shen, Runpu; Pi, Shiqing; Xie, Bin; Huang, Hongjun
Patent: US2002/151742 A1, 2002 ;
反应条件
in N-methyl-acetamide; toluene
参考文献
Takeda Chemical Industries, Ltd.
Patent: US5424478 A1, 1995 ;
反应条件
1.1: hydrobiohenyllithium in THF 1.2: 28 percent / tetrahydrofuran / 0.25 h / -75 °C 2.1: PBr3 / CH2Cl2 / -75 - 25 °C 3.1: 31 percent / DBN / hexane / 6 h / 25 °C View Scheme
参考文献
Rauchschwalbe, Guenter; Zellner, Armin; Schlosser, Manfred
European Journal of Organic Chemistry, 2001 , # 20 p. 3903 - 3909
反应条件
ammonia in water T=50°C; Wittig Reaction; 0.5 h; Product distribution / selectivity;
参考文献
BASF AKTIENGESELLSCHAFT
Patent: WO2005/58811 A1, 2005 ;
Location in patent: Page/Page column 7 ;
反应条件
1: NH4NO3 / methanol / 24 h / 25 °C
2: NaOMe / methanol / 1 h / 25 °C
View Scheme
参考文献
Keana; Boyle; Erion; et al.
Journal of Organic Chemistry, 1983 , vol. 48, # 21 p. 3621 - 3626
反应条件
sodium hydride in tetrahydrofuran
20 h; Ambient temperature;
参考文献
Fleming; Iqbal; Krebs
Tetrahedron, 1983 , vol. 39, # 6 p. 841 - 846
反应条件
1: 76 percent / NaH / tetrahydrofuran / 20 h / Ambient temperature
2: 71 percent / Na2CO3, triethanolamine / ethanol / 3 h / Heating
View Scheme
参考文献
Fleming; Iqbal; Krebs
Tetrahedron, 1983 , vol. 39, # 6 p. 841 - 846
