N-苄氧羰基-L-谷氨酰胺合成路线 （共 50 条）
反应条件
[bis(acetoxy)iodo]benzene in tetrahydrofuran; water T=4°C; Hofmann reaction; 8 h;
参考文献
Andruszkiewicz, Ryszard; Rozkiewicz, Dorota
Synthetic Communications, 2004 , vol. 34, # 6 p. 1049 - 1056
反应条件
ethylenediaminetetraacetic acid; phenyl-methyl-sulfonyl fluoride; water in aq. phosphate buffer T=30°C; Microbiological reactionEnzymatic reaction; Kinetics; Reagent/catalyst;
参考文献
Maurs, Michele; Acher, Francine; Azerad, Robert
Journal of Molecular Catalysis B: Enzymatic, 2012 , vol. 84, p. 22 - 26
反应条件
1: sodium hydrogencarbonate / N,N-dimethyl-formamide / 24 h / 20 °C 2: tert.-butylnitrite / acetonitrile / 1.5 h / |Reflux View Scheme
参考文献
Ottersbach, Philipp A.; Schmitz, Janina; Schnakenburg, Gregor; Guetschow, Michael
Organic Letters, 2013 , vol. 15, # 3 p. 448 - 451
反应条件
1: 67 percent / Ac2O, conc.H2SO4 / acetic acid / 1 h / 50 °C 2: 93 percent / H2, 1N HCl / 10percent Pd-C / methanol; H2O / 1 h View Scheme
参考文献
Eildal, Jonas N. N.; Hultqvist, Greta; Balle, Thomas; Stuhr-Hansen, Nicolai; Padrah, Shahrokh; Gianni, Stefano; Stromgaard, Kristian; Jemth, Per
Journal of the American Chemical Society, 2013 , vol. 135, # 35 p. 12998 - 13007
反应条件
1: 67 percent / Ac2O, conc.H2SO4 / acetic acid / 1 h / 50 °C 2: 93 percent / H2, 1N HCl / 10percent Pd-C / methanol; H2O / 1 h View Scheme
参考文献
Tetrahedron Letters, , vol. 32, # 6 p. 739 - 742
反应条件
acetic anhydride; acetic acid T=50°C; 2 h;
参考文献
Journal of the American Chemical Society, , vol. 135, # 35 p. 12998 - 13007
反应条件
1: 67 percent / Ac2O, conc.H2SO4 / acetic acid / 1 h / 50 °C 2: 93 percent / H2, 1N HCl / 10percent Pd-C / methanol; H2O / 1 h View Scheme
参考文献
Sieber; Riniker
Tetrahedron Letters, 1991 , vol. 32, # 6 p. 739 - 742
反应条件
1: 67 percent / Ac2O, conc.H2SO4 / acetic acid / 1 h / 50 °C 2: 93 percent / H2, 1N HCl / 10percent Pd-C / methanol; H2O / 1 h 4: DCC View Scheme
参考文献
Sieber; Riniker
Tetrahedron Letters, 1991 , vol. 32, # 6 p. 739 - 742
反应条件
phosphorus tribromide in 1,4-dioxane
参考文献
Hirschmann; Schwam; Strachan; Schoenewaldt; Barkemeyer; Miller; Conn; Garsky; Veber; Denkewalter
Journal of the American Chemical Society, 1971 , vol. 93, # 11 p. 2746 - 2754
反应条件
1.1: pyridine; dicyclohexyl-carbodiimide / 2.5 h / 20 °C 1.2: 20 °C 2.1: dihydrogen peroxide; sodium hydroxide / water / 0.5 h / 20 °C 2.2: 0 °C / pH 2 View Scheme
参考文献
Beauchard, Anne; Twum, Elvis A.; Lloyd, Matthew D.; Threadgill, Michael D.
Tetrahedron Letters, 2011 , vol. 52, # 41 p. 5311 - 5314
