1-异丙氧基-4-硝基苯合成路线 （共 19 条）
反应条件
1: isopropyl alcohol With N-benzyl-trimethylammonium hydroxide 0.166667 h; Neat (no solvent); 2: 4-fluoro-nitro-benzene T=70°C; 0.75 h; Neat (no solvent);
参考文献
Meshram; Goud, P. Ramesh; Reddy, B. Chennakesava; Kumar, D. Aravind
Synthetic Communications, 2010 , vol. 40, # 14 p. 2122 - 2129
反应条件
bis(μ-iodo)bis[(-)-sparteine]-dicopper(I); caesium carbonate T=120°C; 12 h;
参考文献
Satyanarayana, Ponnam; Maheswaran, Hariharasarma; Kantam, Mannepalli Lakshmi; Bhargava, Suresh
Bulletin of the Chemical Society of Japan, 2011 , vol. 84, # 7 p. 788 - 790
反应条件
1: With di-tert-butylazodicarboxylate; resin bound PPh3 in dichloromethane T=0°C; Substitution; Mitsunobu reaction; 2: With trifluoroacetic acid in dichloromethane Decarboxylation; elimination; 1 h;
参考文献
ALMIRALL, S.A.; DRACONIS PHARMA, S.L.; LABORATORIOS DEL DR. ESTEVE, S.A.; AGUILAR, Nuria; FERNANDEZ, Joan, Carles; TERRICABRAS, Emma; CARCELLER GONZALEZ, Elena; SALAS SOLANA, Jordi
Patent: WO2013/149997 A1, 2013 ;
Location in patent: Page/Page column 42; 43 ;
反应条件
potassium hydroxide in isopropyl alcohol T=75°C; 7.7 h;
参考文献
Paradisi, Cristina; Quintily, Ugo; Scorrano, Gianfranco
Journal of Organic Chemistry, 1983 , vol. 48, # 18 p. 3022 - 3026
反应条件
in isopropyl alcohol T=75°C; also with the K+ complexing 18-crown-6 ether under anaerobic and aerobic conditions; MechanismProduct distributionRate constant;
参考文献
Arca, Vittorio; Paradisi, Cristina; Scorrano, Gianfranco
Journal of Organic Chemistry, 1990 , vol. 55, # 11 p. 3617 - 3621
反应条件
in ammonia T=-40°C; 24 h;
参考文献
Shtark, A. V.; Kizner, T. A.; Shteingarts, V. D.
Journal of Organic Chemistry USSR (English Translation), 1982 , vol. 18, p. 2051 - 2056
Zhurnal Organicheskoi Khimii, 1982 , vol. 18, # 11 p. 2321 - 2327
反应条件
18-crown-6 ether in isopropyl alcohol T=29.9°C;
参考文献
Prato, Maurizio; Quintily, Ugo; Salvagno, Susanna; Scorrano, Giangranco
Gazzetta Chimica Italiana, 1984 , vol. 114, # 9/10 p. 413 - 416
反应条件
potassium hydroxide; tetrabutylammomium bromide T=75°C;
参考文献
Paradisi, Cristina; Quintily, Ugo; Scorrano, Gianfranco
Journal of Organic Chemistry, 1983 , vol. 48, # 18 p. 3022 - 3026
反应条件
potassium hydroxide; acetophenone in isopropyl alcohol 22 h; Heating;
参考文献
Prato, Maurizio; Quintily, Ugo; Scapol, Lucia; Scorrano, Gianfranco
Bulletin de la Societe Chimique de France, 1987 , # 1 p. 99 - 102
反应条件
tetrachloromethane; nitrogen(IV) oxide
参考文献
Horner; Huebenett
Chemische Berichte, 1952 , vol. 85, p. 804,817
Justus Liebigs Annalen der Chemie, 1953 , vol. 579, p. 193,202
