2-氰基-N,N-二乙基乙酰胺合成路线 （共 13 条）
反应条件
1: With piperidine in isopropyl alcohol 12 - 15 h; Heating / reflux; 2: With acetic acid in isopropyl alcohol T=20°C;
参考文献
WOCKHARDT LIMITED; JAWEED MUKARRAM, Siddiqui, Mohammed; KHAN, Rashid, Abdul, Rehman; YADAV, Ram, Prasad; SHAIKH, Zakir, Gafoor
Patent: WO2005/66117 A1, 2005 ;
Location in patent: Page/Page column 11 ;
反应条件
1.1: LDA / tetrahydrofuran / 2 h / -78 °C
1.2: tetrahydrofuran / 9 h / 20 °C
2.1: 9.2 g / 1-fluoropyridinium trifluoromethanesulfonate / CH2Cl2 / 13 h
View Scheme
参考文献
Yokoyama, Yasuo; Suzuki, Shoko; Furihata, Hyuma; Takahi, Shunsuke; Nomura, Mitsushiro; Kajitani, Masatsugu
Synthesis, 2004 , # 5 p. 701 - 705
反应条件
nitronium tetrafluoroborate in acetonitrile
T=20°C; var. ratio of reactants; Product distribution;
参考文献
Andreev, S. A.; Lebedev, B. A.; Tselinskii, I. V.; Shokhor, I. N.
Journal of Organic Chemistry USSR (English Translation), 1980 , vol. 16, # 7 p. 1159 - 1166
Zhurnal Organicheskoi Khimii, 1980 , vol. 16, # 7 p. 1353 - 1360
