1,2-苯并异噻唑-3-酮合成路线 （共 63 条）
反应条件
chlorine; sodium carbonate
参考文献
Sumitomo Seika Chemicals Co., Ltd.
Patent: US5633384 A1, 1997 ;
反应条件
1: With sulfur; [2,2']bipyridinyl; copper(l) iodide; potassium carbonate in 1-methyl-pyrrolidin-2-one T=110°C; 24 h; Inert atmosphere; 2: With pyridine; N-methoxyamine hydrochloride in 1-methyl-pyrrolidin-2-one T=110°C; 3 h; Inert atmosphere;
参考文献
Krasikova; Katkevics
Chemistry of Heterocyclic Compounds, 2013 , vol. 48, # 11 p. 1684 - 1690
Khim. Geterotsikl. Soedin., 2012 , vol. 48, # 11 p. 1800 - 1807
反应条件
sodium azide; sulfuric acid in dichloromethane 72 h; Ambient temperature;
参考文献
Daich, Abdelali; Decroix, Bernard
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 8 p. 1881 - 1884
反应条件
sodium azide; sulfuric acid in dichloromethane 72 h; Ambient temperature;
参考文献
Daich, Abdelali; Decroix, Bernard
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 8 p. 1881 - 1884
反应条件
in toluene T=100°C; Cyclization; 5 h;
参考文献
Shimizu, Masao; Kikumoto, Hisashi; Konakahara, Takeo; Gama, Yasuo; Shibuya, Isao
Heterocycles, 1999 , vol. 51, # 12 p. 3005 - 3012
反应条件
in toluene T=100°C; 8 h;
参考文献
Shimizu, Masao; Takeda, Ayanobu; Fukazawa, Hidenori; Abe, Yoshimoto; Shibuya, Isao
Heterocycles, 2003 , vol. 60, # 8 p. 1855 - 1864
参考文献
Air Liquide Sante (International)
Patent: EP1225804 B1, 2003 ;
反应条件
1: 68 percent / hydroxylamine-O-sulfonic acid (HOSA); KOH / H2O / 0.5 h / ice bath 2: 28 percent / NaOMe / 3 h / Heating View Scheme
参考文献
Shimizu, Masao; Kikumoto, Hisashi; Konakahara, Takeo; Gama, Yasuo; Shibuya, Isao
Heterocycles, 1999 , vol. 51, # 12 p. 3005 - 3012
反应条件
1: 98 percent / hydroxylamine-O-sulfonic acid (HOSA); KOH / H2O / 0.5 h / ice bath 2: 69 percent / KOH / ethanol / 0.5 h / 20 °C View Scheme
参考文献
Shimizu, Masao; Kikumoto, Hisashi; Konakahara, Takeo; Gama, Yasuo; Shibuya, Isao
Heterocycles, 1999 , vol. 51, # 12 p. 3005 - 3012
反应条件
hydrogenchloride T=100°C;
参考文献
Bryce, Martin R.; Dransfield, Trevor A.; Kandeel, Kamal A.; Vernon, John M.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 2141 - 2144
