1-甲基-2-苯基苯并咪唑合成路线 （共 38 条）
反应条件
triphenylphosphine; silver carbonate; [Pd((diphenylphosphanyl)ferrocene)Cl2]*CH2Cl2 in water
T=60°C; 24 h;
参考文献
Turner, Gemma L.; Morris, James A.; Greaney, Michael F.
Angewandte Chemie - International Edition, 2007 , vol. 46, # 42 p. 7996 - 8000
反应条件
palladium diacetate; copper (II) acetate monohydrate; potassium carbonate; triphenylphosphine in toluene
10 h; Reflux;
参考文献
Yan, Xue-Ming; Mao, Xue-Rong; Huang, Zhi-Zhen
Heterocycles, 2011 , vol. 83, # 6 p. 1371 - 1376
反应条件
1: 2-phenyl-1H-benzimidazole With potassium tert-butylate in tetrahydrofuran
T=20°C; Inert atmosphereSchlenk technique;
2: methyl iodide in tetrahydrofuran
T=20°C; Inert atmosphereSchlenk technique;
参考文献
Rao, Ying-Li; Amarne, Hazem; Chen, Leanne D.; Brown, Matthew L.; Mosey, Nicholas J.; Wang, Suning
Journal of the American Chemical Society, 2013 , vol. 135, # 9 p. 3407 - 3410
反应条件
anhydrous iron chloride; Cu(OAc)2*2H2O; palladium dichloride in N,N-dimethyl-formamide
T=120°C; 24 h;
参考文献
Wu, Xiang-Mei; Shen, Qiu-Xian
Letters in Organic Chemistry, 2013 , vol. 10, # 9 p. 668 - 673
反应条件
sulfur in neat (no solvent)
T=140°C; 16 h; Inert atmosphere;
参考文献
Nguyen, Thanh Binh; Ermolenko, Ludmila; Dean, William A.; Al-Mourabit, Ali
Organic Letters, 2012 , vol. 14, # 23 p. 5948 - 5951
反应条件
palladium 10 on activated carbon in N-dodecane; N,N-dimethyl acetamide
T=120°C; 14 h; Inert atmosphere;
参考文献
Jin, Xukang; Liu, Yuxiao; Lu, Qiongqiong; Yang, Dejun; Sun, Jiangkai; Qin, Shuangshuang; Zhang, Jingwu; Shen, Jiaxuan; Chu, Changhu; Liu, Renhua
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 23 p. 3776 - 3780
反应条件
FeCl3·6H2O in neat (no solvent)
T=130°C; 24 h; Inert atmosphere;
参考文献
Nguyen, Thanh Binh; Bescont, Julie Le; Ermolenko, Ludmila; Al-Mourabit, Ali
Organic Letters, 2013 , vol. 15, # 24 p. 6218 - 6221
反应条件
1: N-methyl-para-phenylenediamine With trimethylaluminum chloride in toluene
T=0 - 20°C;
2: hydroxymethyl JandaJelTM resin-bound benzoyl ester in toluene
24 h; Heating; Further stages.;
参考文献
Matsushita, Hana; Lee, Sang-Hyeup; Joung, Meyoungju; Clapham, Bruce; Janda, Kim D.
Tetrahedron Letters, 2004 , vol. 45, # 2 p. 313 - 316
反应条件
1: With copper (II) acetate monohydrate; pivalic acid sodium salt in N,N-dimethyl-formamide
T=50°C;
2: With oxygen in N,N-dimethyl-formamide
T=120°C;
参考文献
Li, Jihui; Benard, Sebastien; Neuville, Luc; Zhu, Jieping
Organic Letters, 2012 , vol. 14, # 23 p. 5980 - 5983
反应条件
hydrogenchloride; manganese(IV) oxide; 4 A molecular sieve in diethyl ether; toluene
T=105°C; 18 h;
参考文献
Wilfred, Cecilia D.; Taylor, Richard J. K.
Synlett, 2004 , # 9 p. 1628 - 1630
