4-(4-甲基苯基)苯酚合成路线 (共 42 条)
反应条件
potassium carbonate; 10percent Pd/C in water T=20°C; Suzuki-Miyaura coupling reaction; 12 h;
参考文献
Sakurai, Hidehiro; Tsukuda, Tatsuya; Hirao, Toshikazu
Journal of Organic Chemistry, 2002 , vol. 67, # 8 p. 2721 - 2722
反应条件
potassium phosphate; PdCl2(GLCAphos)2/2GLCAphos T=80°C; Substitution; 2 h;
参考文献
Marziale, Alexander N.; Faul, Stefan H.; Reiner, Thomas; Schneider, Sven; Eppinger, Joerg
Green Chemistry, 2010 , vol. 12, # 1 p. 35 - 38
反应条件
potassium carbonate in ethanol; water T=20°C; Suzuki-Miyaura coupling; 5 h;
参考文献
Sreedhar; Yada, Divya; Reddy, P. Surendra
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 14-15 p. 2823 - 2836
反应条件
dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine; potassium fluoride; palladium diacetate in tetrahydrofuran; water T=20°C; Suzuki-Miyaura coupling; 2 h;
参考文献
Ishikawa, Shunpei; Manabe, Kei
Chemistry Letters, 2006 , vol. 35, # 2 p. 164 - 165
反应条件
lithium hydroxide; palladium diacetate in tetrahydrofuran; water T=20°C; Suzuki-Miyaura cross-coupling; 2 h;
参考文献
Ishikawa, Shunpei; Manabe, Kei
Chemical Communications, 2006 , # 24 p. 2589 - 2591
反应条件
palladium diacetate in water; N,N-dimethyl-formamide T=20°C; 5 h;
参考文献
Yamamoto, Yasunori; Takizawa, Miho; Yu, Xiao-Qiang; Miyaura, Norio
Angewandte Chemie - International Edition, 2008 , vol. 47, # 5 p. 928 - 931
反应条件
1: 4-bromo-phenol With tert.-butyl lithium in tetrahydrofuran; diethyl ether; pentane T=-78°C; 0.5 h; 2: With zinc(II) chloride in tetrahydrofuran T=-78 - 20°C; 3: p-trifluoromethanesulfonyloxytoluene With 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl; palladium diacetate in tetrahydrofuran T=20°C; Negishi coupling reaction; 1 h;
参考文献
Shimizu, Haruka; Manabe, Kei
Tetrahedron Letters, 2006 , vol. 47, # 33 p. 5927 - 5931
反应条件
palladium diacetate; caesium carbonate; triphenylphosphine in 1-methyl-pyrrolidin-2-one T=70°C; 15 h; Molecular sieveInert atmosphere;
参考文献
Imahori, Tatsushi; Tokuda, Toru; Taguchi, Tatsuya; Takahata, Hiroki
Organic Letters, 2012 , vol. 14, # 4 p. 1172 - 1175
反应条件
palladium diacetate; caesium carbonate; triphenylphosphine in 1-methyl-pyrrolidin-2-one T=70°C; 15 h; Molecular sieveInert atmosphere; regioselective reaction;
参考文献
Imahori, Tatsushi; Tokuda, Toru; Taguchi, Tatsuya; Takahata, Hiroki
Organic Letters, 2012 , vol. 14, # 4 p. 1172 - 1175
反应条件
oxygen in acetonitrile T=22°C; Flash photolysis;
参考文献
Wang, Yue-Ting; Jin, Kyoung Joo; Leopold, Samuel H.; Wang, Jin; Peng, Huo-Lei; Platz, Matthew S.; Xue, Jiadan; Phillips, David Lee; Glover, Stephen A.; Novak, Michael
Journal of the American Chemical Society, 2008 , vol. 130, # 47 p. 16021 - 16030