1: chloro-diphenylphosphine With diisopropylamine 2: 1-tert-Butyl-2-(methoxymethoxy)benzene With n-butyllithium in diethyl ether T=20°C; 12 h; 3: Compound 5.5; chloro(diisopropylamino)(phenyl)phosphine With hydrogenchloride; Compound 5.2 more than 3 stages;

1.1: N,N,N',N'-tetramethylethylenediamine; n-BuLi / hexane; diethyl ether / 0 °C 1.2: hexane; diethyl ether 2.1: 1.2 g / aq. HCl / tetrahydrofuran / 20 °C View Scheme

1.1: BuLi / tetrahydrofuran; hexane / 2 h / 20 °C 1.2: B(OMe)3 / tetrahydrofuran; hexane / 0.5 h / 0 °C 1.3: 65 percent / aq. NaHCO3; Oxone / acetone / 0.08 h 2.1: 82 percent / aq. HCl / methanol / 1.5 h / 20 °C View Scheme