(S)-(+)-alpha-甲氧基苯乙酸合成路线 （共 41 条）
参考文献
Journal of the American Chemical Society, , vol. 73, p. 3126,3130
反应条件
tert.-butyl lithium; (4S)-2,2'-(1-Ethylpropylidene)bislt;4-(1-methylethyl)-4,5-dihydrooxazolegt; in hexane T=-110 - -78°C; Carboxylation; 5 h; Title compound not separated from byproducts;
参考文献
Tetrahedron Letters, , vol. 40, # 37 p. 6809 - 6812
反应条件
1: lead (IV)-acetate; CHCl3 2: Ag2O View Scheme
参考文献
Journal of the American Chemical Society, , vol. 73, p. 3126,3130
反应条件
water; Candida rugosa lipase in cyclohexane T=45°C; 9 h; Resolution of racemateEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Journal of Molecular Catalysis B: Enzymatic, , vol. 66, # 1-2 p. 113 - 119
反应条件
Candida antarctica lipase B; water in tert-butyl methyl ether T=45°C; 0.8 h; Resolution of racemateEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Journal of Molecular Catalysis B: Enzymatic, , vol. 66, # 1-2 p. 113 - 119
反应条件
water; Candida rugosa lipase in cyclohexane T=45°C; 15.4 h; Resolution of racemateEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Journal of Molecular Catalysis B: Enzymatic, , vol. 66, # 1-2 p. 113 - 119
反应条件
1: 88 percent / AcCl; MeOH / 3 h / Heating 2: H5IO6 / diethyl ether / 0 - 20 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 72, # 4 p. 1174 - 1180
反应条件
ammonium hydroxide; sodium hydroxide; silver nitrate in water; toluene T=20°C; optical yield given as percent ee;
参考文献
Tetrahedron Asymmetry, , vol. 19, # 22 p. 2579 - 2588
反应条件
ruthenium trichloride; sodium periodate
参考文献
Tetrahedron Asymmetry, , vol. 3, # 11 p. 1381 - 1384
参考文献
Journal of the American Chemical Society, , vol. 101, p. 7131 - 7134
