(S)-(+)-alpha-甲氧基苯乙酸合成路线 （共 41 条）
反应条件
2C33H37N*H2O7S2; water T=80°C; 20 h; optical yield given as percent ee;
参考文献
Organic Letters, , vol. 14, # 12 p. 3194 - 3197
反应条件
sodium hydroxide in water T=45°C; 3 h;
参考文献
Journal of Medicinal Chemistry, , vol. 35, # 12 p. 2238 - 2243
反应条件
2,2,6,6-tetramethyl-piperidine-N-oxyl; sodium hypochlorite; sodium chlorite in phosphate buffer; acetonitrile T=55°C; 4 h;
参考文献
Tetrahedron Asymmetry, , vol. 14, # 4 p. 503 - 510
参考文献
Archiv der Pharmazie (Weinheim, Germany), , vol. 270, p. 513,518
Journal of the Chemical Society, , p. 338
反应条件
1: With (R)-BINOL-SnCl4 in dichloromethane; toluene T=-78°C; enantioselective protonation; 1 h; 2: With hydrogenchloride in dichloromethane; toluene Hydrolysis; Further stages. Title compound not separated from byproducts.;
参考文献
Journal of the American Chemical Society, , vol. 122, # 34 p. 8120 - 8130
反应条件
sodium hydroxide in water T=45°C; 3 h; Title compound not separated from byproducts;
参考文献
Journal of Medicinal Chemistry, , vol. 35, # 12 p. 2238 - 2243
反应条件
CSP 9803/5601; trifluoroacetic acid in di-isopropyl ether Resolution of racemate; Product distribution / selectivity;
参考文献
US2004/260081 A1, ;
Page/Page column 7-8 ;
反应条件
1: Ag2O / acetonitrile / Heating 2: KOCl / 15 h / 0 - 20 °C 3: RuCl2*3H2O; H5IO6 / CCl4; acetonitrile; H2O View Scheme
参考文献
Organic Letters, , vol. 3, # 6 p. 823 - 826
反应条件
(S)-HBTM; N-ethyl-N,N-diisopropylamine in toluene T=0°C; 24 h; optical yield given as percent eeenantioselective reaction;
参考文献
Advanced Synthesis and Catalysis, , vol. 351, # 14-15 p. 2301 - 2304
反应条件
water; Candida rugosa lipase in cyclohexane T=45°C; 0.6 h; Resolution of racemateEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Journal of Molecular Catalysis B: Enzymatic, , vol. 66, # 1-2 p. 113 - 119
