2-吡啶-3-基-1,3-苯并噻唑合成路线 （共 17 条）
反应条件
1: tert-butylisonitrile; 2-amino-benzenethiol in N,N-dimethyl-formamide
T=120°C; 24 h; Inert atmosphere;
2: 3-bromo-pyridine With 1,1'-bis-(diphenylphosphino)ferrocene; copper(l) iodide; palladium diacetate; caesium carbonate in N,N-dimethyl-formamide
T=120°C; 24 h; Inert atmosphere;
参考文献
Bochatay, Valentin N.; Boissarie, Patrick J.; Murphy, John A.; Suckling, Colin J.; Lang, Stuart
Journal of Organic Chemistry, 2013 , vol. 78, # 4 p. 1471 - 1477
反应条件
toluene-4-sulfonic acid in PEG-200/400
0.166667 h; Microwave irradiation;
参考文献
Deligeorgiev, Todor G.; Kaloyanova, Stefka; Vasilev, Aleksey; Vaquero, Juan J.
Phosphorus, Sulfur and Silicon and the Related Elements, 2010 , vol. 185, # 11 p. 2292 - 2302
参考文献
Subarowskii; Woronina
Zhurnal Obshchei Khimii, 1953 , vol. 23, p. 140,142; engl. Ausg. S. 139, 140
反应条件
1: SOCl2 / 1 h / 80 °C
2: toluene / 1 h / 20 °C
View Scheme
参考文献
Rudrawar, Santosh; Kondaskar, Atul; Chakraborti, Asit K.
Synthesis, 2005 , # 15 art. no. Z05105SS, p. 2521 - 2526
参考文献
Babichev,F.S. et al.
Sov. Prog. Chem. (Engl. Transl.), 1966 , vol. 32, p. 706 - 715,542 - 550
反应条件
1: benzene
2: 0.25 h / 225 °C
View Scheme
参考文献
Babichev,F.S. et al.
Sov. Prog. Chem. (Engl. Transl.), 1966 , vol. 32, p. 706 - 715,542 - 550
参考文献
E. Lilly and Co.
Patent: US2780628 , 1955 ;
