2-(氯甲氧基)-1,1,1,3,3,3-六氟丙烷合成路线 （共 14 条）
反应条件
thionyl chloride; sulfuric acid T=15 - 35°C;
参考文献
Cr1stalia Productos Quimicos Farmaceuticos LTDA
Patent: US2010/4490 A1, 2010 ;
Location in patent: Page/Page column 5-6 ;
参考文献
Baxter International Inc.
Patent: US5886239 A1, 1999 ;
反应条件
thionyl chloride; sulfuric acid T=15 - 35°C; Product distribution / selectivity;
参考文献
Cr1stalia Productos Quimicos Farmaceuticos LTDA
Patent: US2010/4490 A1, 2010 ;
Location in patent: Page/Page column 4 ;
反应条件
1: With AlCl3, aluminium chloride T=20 - 30°C; 10 h; 2: With hydrogenchloride in water T=0°C; Product distribution / selectivity;
参考文献
Lunan Pharmaceutical Group Corporation
Patent: US2011/105803 A1, 2011 ;
Location in patent: Page/Page column 3-4 ;
反应条件
1: hexafluoroisopropyl alcohol With AlCl3, aluminium chloride T=0°C; 1 h; 2: metaformaldehyde T=0 - 20°C; 5 h; Cooling with ice;
参考文献
Moghimi; Khavassi; Benvidi; Vojdani; Faghihimoghaddam
Journal of the Iranian Chemical Society, 2011 , vol. 8, # 4 p. 958 - 964
反应条件
thionyl chloride; sulfuric acid T=15 - 35°C; 6 h; Product distribution / selectivity;
参考文献
CRISTALIA PRODUTOS QUIMICOS FARMACEUTICOS LTDA.
Patent: WO2008/37040 A2, 2008 ;
Location in patent: Page/Page column 20-22 ;
反应条件
thionyl chloride; sulfuric acid T=15 - 35°C; 6 h; Product distribution / selectivity;
参考文献
CRISTALIA PRODUTOS QUIMICOS FARMACEUTICOS LTDA.
Patent: WO2008/37039 A2, 2008 ;
Location in patent: Page/Page column 17-21 ;
反应条件
chlorine Irradiation;
参考文献
Speers,L. et al.
Journal of Medicinal Chemistry, 1971 , vol. 14, p. 593 - 595
反应条件
aluminium trichloride T=0 - 20°C; Etherification;
参考文献
Bieniarz, Christopher; Behme, Chris; Ramakrishna, Kornepati
Journal of Fluorine Chemistry, 2000 , vol. 106, # 1 p. 99 - 102
反应条件
hydrogenchloride; potassium fluoride; water; Aliquat HTA-1 T=100°C; 3 h; Product distribution / selectivity;
参考文献
WO2006/55748 A2, ;
Page/Page column 12 ;
