2-(三苯基膦亚基)丙酸甲酯合成路线 （共 32 条）
反应条件
sodium hydroxide in water
参考文献
Elemes, Yiannis; Foote, Christopher S.
Journal of the American Chemical Society, 1992 , vol. 114, # 15 p. 6044 - 6050
反应条件
sodium hydroxide in dichloromethane; water Dehydroiodination;
参考文献
Werkhoven, Thekla M.; Van Nispen, Reinier; Lugtenburg, Johan
European Journal of Organic Chemistry, 1999 , # 11 p. 2909 - 2914
反应条件
1: 80 percent / ethyl acetate / 24 h / Heating 2: Et3N; molecular sieves 3 Angstroem / CH2Cl2 / 0.5 h / 20 °C View Scheme
参考文献
Eey, Stanley T.-C.; Lear, Martin J.
Organic Letters, 2010 , vol. 12, # 23 p. 5510 - 5513
参考文献
Henrot, Matthias; Richter, Martin E.A.; Maddaluno, Jacques; Hertweck, Christian; De Paolis, Michael
Angewandte Chemie - International Edition, 2012 , vol. 51, # 38 p. 9587 - 9591
Angew. Chem., 2012 , vol. 124, # 38 p. 9725 - 9729,5
反应条件
1: 85 percent / CH2Cl2 / 20 °C 2: 100 percent / NaOH / CH2Cl2; H2O View Scheme
参考文献
Bestmann,H.J.; Schulz,H.
Chemische Berichte, 1962 , vol. 95, p. 2921 - 2927
反应条件
1: 100 percent / NaOH / CH2Cl2; H2O 2: 85 percent / CH2Cl2 / 20 °C 3: 100 percent / NaOH / CH2Cl2; H2O View Scheme
参考文献
Werkhoven, Thekla M.; Van Nispen, Reinier; Lugtenburg, Johan
European Journal of Organic Chemistry, 1999 , # 11 p. 2909 - 2914
反应条件
potassium tert-butylate 1.) CH2Cl2, reflux, 1 h, 2.) CH2Cl2, THF, RT, 30 min; Yield givenMultistep reaction;
参考文献
Xie, Lan; Takeuchi, Yasuo; Cosentino, L. Mark; Lee, Kuo-Hsiung
Journal of Medicinal Chemistry, 1999 , vol. 42, # 14 p. 2662 - 2672
反应条件
(i) benzene, (ii) aq. NaOH; Multistep reaction;
参考文献
Stotter,P.L.; Hill,K.A.
Tetrahedron Letters, 1975 , p. 1679 - 1682
反应条件
4-methoxy-phenol in water; pentane Wittig reaction;
参考文献
Werkhoven, Thekla M.; Van Nispen, Reinier; Lugtenburg, Johan
European Journal of Organic Chemistry, 1999 , # 11 p. 2909 - 2914
反应条件
in benzene 6 h; Heating;
参考文献
Argyropoulos, N. G.; Gallos, J. K.; Nicolaides, D. N.
Tetrahedron, 1986 , vol. 42, # 13 p. 3631 - 3636
