N-[(1S)-1-(羟基甲基)-2-氧代-2-[(苯基甲氧基)氨基]乙基]-氨基甲酸叔丁酯合成路线 （共 5 条）
反应条件
dicyclohexyl-carbodiimide in tetrahydrofuran T=0 - 20°C; Inert atmosphere;
参考文献
Sliwa, Aline; Dive, Georges; Habib Jiwan, Jean-Louis; Marchand-Brynaert, Jacqueline
Tetrahedron, 2010 , vol. 66, # 49 p. 9519 - 9527
反应条件
lithium hexamethyldisilazane in tetrahydrofuran T=-78°C;
参考文献
Gissot, Arnaud; Volonterio, Alessandro; Zanda, Matteo
Journal of Organic Chemistry, 2005 , vol. 70, # 17 p. 6925 - 6928
反应条件
dicyclohexyl-carbodiimide in tetrahydrofuran; water 3 h; pH 4.5;
参考文献
Mattingly, Phillip G.; Miller, Marvin J.
Journal of Organic Chemistry, 1980 , vol. 45, # 3 p. 410 - 415
反应条件
1: 62 percent / Ph3P, diethyl azodicarboxylate / tetrahydrofuran / 6 h / 50 °C 2: 100 percent / H2 / 10percent Pd/C / methanol / 0.75 h / 760 Torr View Scheme
参考文献
Mattingly, Phillip G.; Miller, Marvin J.
Journal of Organic Chemistry, 1980 , vol. 45, # 3 p. 410 - 415
反应条件
tetrachloromethane; TEA; triphenylphosphine in acetonitrile
参考文献
Xu; Miller
Journal of Organic Chemistry, 1998 , vol. 63, # 13 p. 4314 - 4322
