5-(4-氯苯基)-2,4-二氢-[1,2,4]-三唑-3-硫酮合成路线 （共 9 条）
反应条件
sodium hydroxide in methanol Reflux;
参考文献
Murty; Ram, Kesur R.; Rao, Rayudu Venkateswara; Yadav; Rao, Janapala Venkateswara; Pamanji; Velatooru
Letters in Drug Design and Discovery, 2012 , vol. 9, # 3 p. 276 - 281
反应条件
1: pyridine / Ambient temperature 2: 1M NaHCO3 / H2O / 17 h / Heating View Scheme
参考文献
Tozkoparan, Birsen; Kilcigil, Guelguen Ayhan; Ertan, Rahmiye; Ertan, Mevluet; Kelicen, Pelin; Demirdamar, Ruemeysa
Arzneimittel-Forschung/Drug Research, 1999 , vol. 49, # 12 p. 1006 - 1011
反应条件
T=200°C; 0.333333 h;
参考文献
Malbec, Frederique; Milcent, Rene; Barbier, Geo
Journal of Heterocyclic Chemistry, 1984 , vol. 21, p. 1689 - 1698
反应条件
1: hydrazine hydrate / methanol / Reflux 2: hydrogenchloride / methanol / 1 h / Reflux 3: sodium hydroxide / methanol / Reflux View Scheme
参考文献
Murty; Ram, Kesur R.; Rao, B. Ramalingeswara; Rao, Rayudu Venkateswara; Katiki, Mohana Rao; Rao, Janapala Venkateswara; Pamanji; Velatooru
Medicinal Chemistry Research, 2014 , vol. 23, # 4 p. 1661 - 1671
反应条件
1: hydrogenchloride / methanol / 1 h / Reflux 2: sodium hydroxide / methanol / Reflux View Scheme
参考文献
Murty; Ram, Kesur R.; Rao, B. Ramalingeswara; Rao, Rayudu Venkateswara; Katiki, Mohana Rao; Rao, Janapala Venkateswara; Pamanji; Velatooru
Medicinal Chemistry Research, 2014 , vol. 23, # 4 p. 1661 - 1671
反应条件
1: sulfuric acid / 4 h / Reflux 2: hydrazine hydrate / methanol / Reflux 3: hydrogenchloride / methanol / 1 h / Reflux 4: sodium hydroxide / methanol / Reflux View Scheme
参考文献
Murty; Ram, Kesur R.; Rao, B. Ramalingeswara; Rao, Rayudu Venkateswara; Katiki, Mohana Rao; Rao, Janapala Venkateswara; Pamanji; Velatooru
Medicinal Chemistry Research, 2014 , vol. 23, # 4 p. 1661 - 1671
反应条件
1: 58 percent / dimethylformamide / 20 h / Ambient temperature 2: 20 percent / 0.33 h / 200 °C View Scheme
参考文献
Malbec, Frederique; Milcent, Rene; Barbier, Geo
Journal of Heterocyclic Chemistry, 1984 , vol. 21, p. 1689 - 1698
参考文献
Hoggarth
Journal of the Chemical Society, 1949 , p. 1163,1167
Journal of the Chemical Society, 1950 , p. 1579,1581
参考文献
Hoggarth
Journal of the Chemical Society, 1950 , p. 612
