(2S,5R)-1-苄基-2,5-二甲基哌嗪合成路线 （共 3 条）
反应条件
hydrogenchloride in 1,4-dioxane; dichloromethane 1 h; Product distribution / selectivity;
参考文献
PFIZER INC.
Patent: WO2008/125945 A2, 2008 ;
Location in patent: Page/Page column 20; 22 ;
WO 2008/125945 A2
参考文献
PFIZER INC.
Patent: WO2008/96260 A1, 2008 ;
Location in patent: Page/Page column 41 ;
WO 2008/096260 A1
反应条件
hydrogenchloride; borane; N-ethyl-N,N-diisopropylamine in tetrahydrofuran; methanol; diethyl ether; hexane; dichloromethane; chloroform; acetone
参考文献
ELI LILLY AND COMPANY
Patent: EP1204654 B1, 2003 ;
EP 1204654 B1
