3,4,5-三氯噻吩-2-羧酸合成路线 （共 10 条）
反应条件
sulfuric acid in water; acetic acid 0.5 h; Heating;
参考文献
Kon'kova, S. G.; Safaryan, A. A.; Akopyan, A. N.
Journal of Organic Chemistry USSR (English Translation), 1982 , vol. 18, # 2 p. 348 - 351
Zhurnal Organicheskoi Khimii, 1982 , # 2 p. 400 - 403
反应条件
n-butyllithium; diethyl ether Behandeln der Reaktionsloesung mit Kohlendioxid;
参考文献
Journal of the American Chemical Society, , vol. 70, p. 2378
反应条件
water; hydrogen cation
参考文献
Rahman, M. T.
Journal of the Indian Chemical Society, 1981 , vol. 58, p. 21 - 23
反应条件
n-butyllithium 1.) -78 deg C, 3 h, THF; 2.) -78 deg C to RT; Yield given. Multistep reaction;
参考文献
Monatshefte fuer Chemie, , vol. 114, p. 249 - 254
反应条件
n-butyllithium multistep; 1.) THF, -78 deg C, 18 h; various conc. of n-BuLi, t-BuLi instead n-Buli, further solvent and temp.; Product distribution;
参考文献
Monatshefte fuer Chemie, , vol. 114, p. 249 - 254
反应条件
nickel in ethanol 27 h; Heating; Product distribution;
参考文献
Kon'kova, S. G.; Safaryan, A. A.; Akopyan, A. N.
Journal of Organic Chemistry USSR (English Translation), 1982 , vol. 18, # 2 p. 348 - 351
Zhurnal Organicheskoi Khimii, 1982 , # 2 p. 400 - 403
反应条件
palladium (II) trifluoroacetate; silver carbonate in dimethyl sulfoxide; N,N-dimethyl-formamide T=120°C; 16 h; Inert atmosphere;
参考文献
Cornella, Josep; Lahlali, Hicham; Larrosa, Igor
Chemical Communications, 2010 , vol. 46, # 43 p. 8276 - 8278
反应条件
acetic acid; silver carbonate in dimethyl sulfoxide T=120°C; 16 h;
参考文献
Lu, Pengfel; Sanchez, Carolina; Cornella, Josep; Larrosa, Igor
Organic Letters, 2009 , vol. 11, # 24 p. 5710 - 5713
反应条件
palladium (II) trifluoroacetate; silver carbonate in dimethyl sulfoxide; N,N-dimethyl-formamide T=120°C; 16 h; Inert atmosphere;
参考文献
Cornella, Josep; Lahlali, Hicham; Larrosa, Igor
Chemical Communications, 2010 , vol. 46, # 43 p. 8276 - 8278
反应条件
thionyl chloride in N,N-dimethyl-formamide
