sodium metaphosphate; Raney nickel W4 in pyridine; water; acetic acid T=20°C; 2.5 h;

lead(IV) acetate; lead dioxide in acetic acid 72 h; Ambient temperature;

hydrogenchloride; diethyl ether Behandeln des entstandenden Imid-Hydrochlorids mit Wasser;

1: 81 percent / KOt-Bu / tetrahydrofuran 2: 100 percent / H2 / 1 percent Pd/C / ethanol; ethyl acetate 3: 100 percent / TFA / CH2Cl2 4: 84 percent / aq. LiOH / tetrahydrofuran 5: 100 percent / TFA View Scheme

lithium hydroxide in methanol Heating;