1,2:5,6-二异亚丙基-α-D-异呋喃糖合成路线 （共 19 条）
反应条件
sodium tetrahydroborate in ethanol T=0 - 20°C; 2 h;
参考文献
Deshmukh, Abdul Rakeeb A. S.; Jayanthi, Arumugam; Thiagarajan, Kamanan; Puranik, Vedavati G.; Bhawal, Baburao M.
Synthesis, 2004 , # 18 p. 2965 - 2974
反应条件
1: With oxalyl dichloride; dimethyl sulfoxide; triethylamine in dichloromethane T=-78°C; 2: With sodium tetrahydroborate in methanol T=0°C;
参考文献
Ghosh, Subhash; Shashidhar; Dutta, Samit Kumar
Tetrahedron Letters, 2006 , vol. 47, # 34 p. 6041 - 6044
反应条件
water; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate in acetonitrile T=75°C; 0.5 h;
参考文献
Ramasamy, Kanda S.; Averett, Devron
Synlett, 1999 , # 6 p. 709 - 712
反应条件
iodine in methanol T=20°C; ether cleavage; 1 h;
参考文献
Ramasamy, Kanda S.; Bandaru, Rajanikanth; Averett, Devron
Synthetic Communications, 1999 , vol. 29, # 16 p. 2881 - 2894
反应条件
1: 68 percent / ZnCl2; aq. H3PO4 / 36 h / 20 °C 2: 91 percent / pyridinium dichromate; acetic anhydride / CH2Cl2 / 4 h / 75 °C 3: 90 percent / NaBH4 / ethanol; H2O / 1 h / 0 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 124, # 36 p. 10642 - 10643
反应条件
sodium tetrahydroborate in methanol
参考文献
Loiseleur, Olivier; Ritson, Dougal; Nina, Mafalda; Crowley, Patrick; Wagner, Trixie; Hanessian, Stephen
Journal of Organic Chemistry, 2007 , vol. 72, # 17 p. 6353 - 6363
反应条件
1: 32 percent / ZnCl2; H3PO4 / 30 h / 20 °C 2: 85 percent / PCC; 3 Angstroem molecular sieves; neutral alumina / CH2Cl2 / 15 h / 20 °C 3: 96 percent / NaBH4 / aq. ethanol / 2 h / 0 - 20 °C View Scheme
参考文献
Synthesis, , # 18 p. 2965 - 2974
反应条件
1.1: sodium hydride / N,N-dimethyl-formamide / 0.33 h / 0 °C 1.2: 2 h 2.1: acetic acid / 16 h / 20 °C 3.1: sodium periodate / 1,4-dioxane / 1.5 h / 20 °C View Scheme
参考文献
ISIS PHARMACEUTICALS, INC.; SETH, Punit, P.; SWAYZE, Eric, E.; HANESSIAN, Stephen; SCHROEDER, Benjamin, R.; GIACOMETTI, Robert, D.; MERNER, Bradley, L.
Patent: WO2013/154798 A1, 2013 ;
反应条件
1: With sulfuryl dichloride in dichloromethane T=-5 - 0°C; 0.666667 h; Inert atmosphere; 2: With 1,2,3-Benzotriazole in dichloromethane T=20°C; 6.5 h; Inert atmosphere;
参考文献
Azad, Chandra S.; Saxena, Anil K.
Tetrahedron, 2013 , vol. 69, # 12 p. 2608 - 2612
反应条件
1: AcOH, H2O / 6.5 h / Ambient temperature 2: 98 percent / NaIO4, H2O, NaHCO3 / 1.67 h / Ambient temperature 3: 98 percent / Amberlite IR-120 (H(+)-form), H2O / 2.5 h / 45 °C 4: 64 percent / NaBH4, H2O / 0.5 h / Ambient temperature View Scheme
参考文献
Miculka, Christian
Synlett, 1999 , # SPEC. ISS. p. 948 - 950
