2,6-二氟-3-硝基-乙酰苯胺合成路线 （共 2 条）
反应条件
sulfuric acid; nitric acid T=20°C;
参考文献
Hanson, James R.; Saberi, Hamid
Journal of Chemical Research, 2004 , # 10 p. 699 - 701
反应条件
1.1: hydrogen / palladium 10 on activated carbon / methanol / 3 h / 10343.2 Torr / autoclave
2.1: pyridine / dichloromethane / 16 h / 20 °C
3.1: hydrogenchloride / ethanol; water / 2 h / 80 °C
3.2: pH 6
View Scheme
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; STADTMUELLER, Heinz
Patent: WO2012/104388 A1, 2012 ;
WO 2012/104388 A1
