1-甲基-5-硝基-1H-苯并三唑合成路线 （共 4 条）
反应条件
1: With hydrogenchloride; sodium nitrite in water T=0°C; 3 h; 2: With potassium hydroxide in water
参考文献
METHYLGENE INC.
Patent: WO2005/92899 A1, 2005 ;
Location in patent: Page/Page column 155 ;
反应条件
sodium ethanolate in ethanol 24 h; Heating;
参考文献
Caliendo; Novellino; Sagliocco; Santagada; Silipo; Vittoria
European Journal of Medicinal Chemistry, 1992 , vol. 27, # 2 p. 161 - 166
反应条件
sodium hydroxide in water 1.) room temperature, 0.5 h, 2.) 0 deg C, 1.5 h;
参考文献
Katritzky, Alan R.; Yannakopoulou, Konstantina
Heterocycles, 1989 , vol. 28, # 2 p. 1121 - 1134
参考文献
Brady; Reynolds
Journal of the Chemical Society, 1930 , p. 2667,2671,2673
