5-苯基-1H-吡嗪-2-酮合成路线 （共 15 条）
反应条件
sodium hydroxide; sodium hydrogencarbonate in hydrogenchloride; methanol
参考文献
McNeil Laboratories, Incorporated
Patent: US4046763 A1, 1977 ;
反应条件
potassium hydroxide in methanol 1 h; Heating;
参考文献
Ohta, Akihiro; Watanabe, Tokuhiro; Akita, Yasuo; Yoshida, Maki; Toda, Suzumi; et al.
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 1061 - 1067
参考文献
Watanabe, Tokuhiro; Tanaka, Yukiko; Sekiya, Kohko; Akita, Yasuo; Ohta, Akihiro
Synthesis, 1980 , # 1 p. 39 - 41
反应条件
1: 34 percent / KOH / ethanol / 5 h / Heating 2: 76 percent / 90percent H2O2, maleic anhydride / CH2Cl2 / 1) r.t., overnight, 2) reflux, 2 h 3: 1 h / Heating 4: 10percent KOH / methanol / 1 h / Heating View Scheme
参考文献
Ohta, Akihiro; Watanabe, Tokuhiro; Akita, Yasuo; Yoshida, Maki; Toda, Suzumi; et al.
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 1061 - 1067
反应条件
1: 76 percent / 90percent H2O2, maleic anhydride / CH2Cl2 / 1) r.t., overnight, 2) reflux, 2 h 2: 1 h / Heating 3: 10percent KOH / methanol / 1 h / Heating View Scheme
参考文献
Ohta, Akihiro; Watanabe, Tokuhiro; Akita, Yasuo; Yoshida, Maki; Toda, Suzumi; et al.
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 1061 - 1067
反应条件
1: 1 h / Heating 2: 10percent KOH / methanol / 1 h / Heating View Scheme
参考文献
Ohta, Akihiro; Watanabe, Tokuhiro; Akita, Yasuo; Yoshida, Maki; Toda, Suzumi; et al.
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 1061 - 1067
反应条件
1: Me3SiCl / 0.5 h / Heating 2: PBr3 / 1 h / 150 °C View Scheme
参考文献
Sato, Nobuhiro; Narita, Nobuhiko
Journal of Heterocyclic Chemistry, 1999 , vol. 36, # 3 p. 783 - 786
反应条件
1: POCl3, PCl5 / 1 h / 160 °C 2: 25 percent / 90percent H2O2, maleic anhydride / CHCl3 / 1) r.t., overnight, 2) reflux, 3 h 3: POCl3 / 0.5 h / Heating View Scheme
参考文献
Ohta, Akihiro; Watanabe, Tokuhiro; Akita, Yasuo; Yoshida, Maki; Toda, Suzumi; et al.
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 1061 - 1067
反应条件
sulfuric acid; trichlorophosphate
参考文献
Ohta, Akihiro; Watanabe, Tokuhiro; Akita, Yasuo; Yoshida, Maki; Toda, Suzumi; et al.
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 1061 - 1067
反应条件
1: Me3SiCl / 0.5 h / Heating
2: phosphorus triiodide / 1,1,2-trichloro-ethane / 24 h / Heating
View Scheme
参考文献
Sato, Nobuhiro; Narita, Nobuhiko
Journal of Heterocyclic Chemistry, 1999 , vol. 36, # 3 p. 783 - 786
