1-甲基-4-苯基-1H-喹啉-2-酮合成路线 （共 30 条）
反应条件
in tetrahydrofuran; dichloromethane
T=0 - 20°C; Cycloaddition; Cycloreversion; Oxidation; 2 h;
参考文献
Quast, Helmut; Ivanova, Svetlana; Peters, Eva-Maria; Peters, Karl
European Journal of Organic Chemistry, 2000 , # 3 p. 507 - 520
反应条件
in dichloromethane; benzene
T=0 - 20°C; Cycloaddition; Cycloreversion; Oxidation; 2 h;
参考文献
Quast, Helmut; Ivanova, Svetlana; Peters, Eva-Maria; Peters, Karl
European Journal of Organic Chemistry, 2000 , # 3 p. 507 - 520
反应条件
1: 4 percent / hydroquinone / benzene / 24 h / 190 °C
2: 55 percent / hydroquinone / benzene / 24 h / 220 °C
View Scheme
参考文献
Kaupp, Gerd; Gruendken, Eleonore; Matthies, Doris
Chemische Berichte, 1986 , vol. 119, # 10 p. 3109 - 3120
反应条件
1: 48 percent / 2 h / 170 °C
2: 88 percent / NaH / dimethylsulfoxide / Ambient temperature
3: 55 percent / hydroquinone / benzene / 24 h / 220 °C
View Scheme
参考文献
Kaupp, Gerd; Gruendken, Eleonore; Matthies, Doris
Chemische Berichte, 1986 , vol. 119, # 10 p. 3109 - 3120
反应条件
1: 88 percent / NaH / dimethylsulfoxide / Ambient temperature
2: 55 percent / hydroquinone / benzene / 24 h / 220 °C
View Scheme
参考文献
Kaupp, Gerd; Gruendken, Eleonore; Matthies, Doris
Chemische Berichte, 1986 , vol. 119, # 10 p. 3109 - 3120
反应条件
1: water; sodium hydroxide / methanol / 16 h / 100 °C / |Inert atmosphere
2: palladium (II) bromide; triphenylphosphine; silver(I) acetate / toluene; N,N-dimethyl acetamide / 1 h / 150 °C / |Sealed tube; |Inert atmosphere; |Microwave irradiation; |Schlenk technique
View Scheme
参考文献
Carrer, Amandine; Brion, Jean-Daniel; Messaoudi, Samir; Alami, Mouad
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 10 p. 2044 - 2054
反应条件
1.1: triethylamine / dichloromethane / 5 h / 0 - 20 °C / |Inert atmosphere
1.2: 20 °C / |Inert atmosphere
2.1: water; sodium hydroxide / methanol / 16 h / 100 °C / |Inert atmosphere
3.1: palladium (II) bromide; triphenylphosphine; silver(I) acetate / toluene; N,N-dimethyl acetamide / 1 h / 150 °C / |Sealed tube; |Inert atmosphere; |Microwave irradiation; |Schlenk technique
View Scheme
参考文献
Carrer, Amandine; Brion, Jean-Daniel; Messaoudi, Samir; Alami, Mouad
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 10 p. 2044 - 2054
反应条件
in tetrahydrofuran; dichloromethane
T=0 - 20°C; Cycloaddition; Cycloreversion; Oxidation; 2 h; Title compound not separated from byproducts;
参考文献
Quast, Helmut; Ivanova, Svetlana; Peters, Eva-Maria; Peters, Karl
European Journal of Organic Chemistry, 2000 , # 3 p. 507 - 520
反应条件
in tetrahydrofuran; dichloromethane
T=0 - 20°C; Cycloaddition; Cycloreversion; Oxidation; 2 h; Title compound not separated from byproducts;
参考文献
Quast, Helmut; Ivanova, Svetlana; Peters, Eva-Maria; Peters, Karl
European Journal of Organic Chemistry, 2000 , # 3 p. 507 - 520
反应条件
T=60 - 88°C; Rate constant;
参考文献
Koelsch; Britain
Journal of Organic Chemistry, 1959 , vol. 24, p. 1551
