1-甲基-4-苯基-1H-喹啉-2-酮合成路线 （共 30 条）
反应条件
copper diacetate; palladium diacetate in acetonitrile
T=110°C; P=2068.65 Torr; 20 h; Autoclave;
参考文献
Ferguson, Jamie; Zeng, Fanlong; Alwis, Natacha; Alper, Howard
Organic Letters, 2013 , vol. 15, # 8 p. 1998 - 2001
反应条件
potassium phosphate; CM-phos; palladium diacetate; triethylamine in tert-butyl alcohol
T=50°C; Suzuki coupling; 2 h; Inert atmosphere;
参考文献
Wong, Pui Yu; Chow, Wing Kin; Chung, Kin Ho; So, Chau Ming; Lau, Chak Po; Kwong, Fuk Yee
Chemical Communications, 2011 , vol. 47, # 29 p. 8328 - 8330
反应条件
triethylamine; triphenylphosphine; palladium diacetate in ethylene glycol dimethyl ether; water
T=150°C; Suzuki cross-coupling; 0.5 h; microwave irradiation;
参考文献
Glasnov, Toma N.; Stadlbauer, Wolfgang; Kappe, C. Oliver
Journal of Organic Chemistry, 2005 , vol. 70, # 10 p. 3864 - 3870
反应条件
potassium acetate; trans-di(μ-acetato)bis{o-(d-o-tolylphosphino)benzyl}Pd2 in various solvent(s)
T=125°C; 0.75 h; microwave irradiation;
参考文献
Arshad, Nuzhat; Hashim, Jamshed; Kappe, C. Oliver
Journal of Organic Chemistry, 2008 , vol. 73, # 12 p. 4755 - 4758
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=70°C; 0.5 h;
参考文献
Park, Kwanghee Koh; Lee, Jin Joo
Tetrahedron, 2004 , vol. 60, # 13 p. 2993 - 2999
反应条件
silver(I) acetate; palladium diacetate; trifluoroacetic acid
T=110°C; 24 h; Inert atmosphere;
参考文献
Tang, Dong-Jun; Tang, Bo-Xiao; Li, Jin-Heng
Journal of Organic Chemistry, 2009 , vol. 74, # 17 p. 6749 - 6755
反应条件
hydroquinone in benzene
T=220°C; 24 h;
参考文献
Kaupp, Gerd; Gruendken, Eleonore; Matthies, Doris
Chemische Berichte, 1986 , vol. 119, # 10 p. 3109 - 3120
反应条件
sodium hydride in tetrahydrofuran
2 h; Heating;
参考文献
Park, Kwanghee Koh; Lee, Jin Joo
Tetrahedron, 2004 , vol. 60, # 13 p. 2993 - 2999
反应条件
sodium hydride in dimethyl sulfoxide
Ambient temperature;
参考文献
Kaupp, Gerd; Gruendken, Eleonore; Matthies, Doris
Chemische Berichte, 1986 , vol. 119, # 10 p. 3109 - 3120
反应条件
1: 82 percent / phosphorus oxychloride / dioxane / 0.42 h / 120 °C / microwave irradiation
2: 83 percent / triethylamine; PPh3 / Pd(OAc)2 / 1,2-dimethoxy-ethane; H2O / 0.5 h / 150 °C / microwave irradiation
View Scheme
参考文献
Glasnov, Toma N.; Stadlbauer, Wolfgang; Kappe, C. Oliver
Journal of Organic Chemistry, 2005 , vol. 70, # 10 p. 3864 - 3870
