4-甲基-3-甲基硫代-5-苯基-4H-1,2,4-噻唑合成路线 (共 4 条)
反应条件
sodium hydroxide in ethanol Ambient temperature;
参考文献
Kane; Staeger; Dalton; Miller; Dudley; Ogden; Kehne; Ketteler; McCloskey; Senyah; Chmielewski
Journal of Medicinal Chemistry, 1994 , vol. 37, # 1 p. 125 - 132
反应条件
1: 60 percent / 1M aq. NaHCO3 / 24 h / Heating 2: 72 percent / aq. NaOH / ethanol / Ambient temperature View Scheme
参考文献
Hoggarth
Journal of the Chemical Society, 1949 , p. 1918,1922
反应条件
1: 69 percent / tetrahydrofuran / 2 h / Heating 2: 60 percent / 1M aq. NaHCO3 / 24 h / Heating 3: 72 percent / aq. NaOH / ethanol / Ambient temperature View Scheme
参考文献
Kane; Staeger; Dalton; Miller; Dudley; Ogden; Kehne; Ketteler; McCloskey; Senyah; Chmielewski
Journal of Medicinal Chemistry, 1994 , vol. 37, # 1 p. 125 - 132
反应条件
3-chloro-benzenecarboperoxoic acid in dichloromethane 17 h;
参考文献
Journal of Medicinal Chemistry, , vol. 37, # 1 p. 125 - 132