4H-环戊并[2,1-B:3,4-B']二噻吩-4-酮合成路线 （共 17 条）
反应条件
1.1: n-butyllithium / diethyl ether; hexane / 0.5 h / -78 °C 1.2: -78 - 20 °C 2.1: pyridinium chlorochromate / dichloromethane / 12 h / 20 °C 3.1: copper / N,N-dimethyl-formamide / 15 h / Reflux View Scheme
参考文献
Macromolecules, , vol. 43, # 2 p. 697 - 708
反应条件
1.1: 66 percent / TMSOTf / CH2Cl2 / 3 h / 20 °C 2.1: n-BuLi; I2 2.2: 90 percent / Cu / dimethylformamide / 15 h / Heating 3.1: 91 percent / aq. HCl View Scheme
参考文献
Synthesis, , # 9 p. 1253 - 1258
反应条件
1.1: n-BuLi; I2 1.2: 90 percent / Cu / dimethylformamide / 15 h / Heating 2.1: 91 percent / aq. HCl View Scheme
参考文献
Synthesis, , # 9 p. 1253 - 1258
反应条件
potassium hydroxide; hydrazine in ethylene glycol T=190°C; 13 h;
参考文献
Osaka University; Sumitomo Chemical Company, Limited
Patent: EP1997821 A1, 2008 ;
Location in patent: Page/Page column 32 ;
反应条件
1: hydrazine hydrate; potassium hydroxide / ethylene glycol / 8 h / 180 °C / Inert atmosphere
2: potassium iodide; potassium hydroxide / dimethyl sulfoxide / 16 h / 0 - 20 °C
3: N-bromosuccinmide / N,N-dimethyl-formamide / 12 h / 20 °C / Inert atmosphere; Darkness
View Scheme
参考文献
Chen, Chiu-Hsiang; Hsieh, Chao-Hsiang; Dubosc, Martin; Cheng, Yen-Ju; Hsu, Chain-Shu
Macromolecules, 2010 , vol. 43, # 2 p. 697 - 708
反应条件
1: 65 percent / potassium hydroxide; hydrazine hydrate / ethane-1,2-diol / 8 h / 180 °C
2: 85 percent / potassium hydroxide; potassium iodide / dimethylsulfoxide / 20 °C
3: N-bromosuccinimide / dimethylformamide / 20 °C
View Scheme
参考文献
Coppo, Paolo; Cupertino, Domenico C.; Yeates, Stephen G.; Turner, Michael L.
Journal of Materials Chemistry, 2002 , vol. 12, # 9 p. 2597 - 2599
反应条件
1: 65 percent / potassium hydroxide; hydrazine hydrate / ethane-1,2-diol / 8 h / 180 °C
2: potassium hydroxide; potassium iodide / dimethylsulfoxide
3: N-bromosuccinimide / dimethylformamide
View Scheme
参考文献
Coppo, Paolo; Cupertino, Domenico C.; Yeates, Stephen G.; Turner, Michael L.
Macromolecules, 2003 , vol. 36, # 8 p. 2705 - 2711
