N-苄氧羰基-L-苯丙氨酸对硝基苯酯合成路线 （共 26 条）
反应条件
1: 75 percent / ethyl acetate / 2 h 2: 280 mg / H2 / 1 percent PdCl2 / ethanol / 10 h 3: 10 percent NaOH / 4 h 4: 58 percent / pyridine / 1 h / 90 °C 5: 3 percent KOH / ethanol / 1 h / Heating View Scheme
参考文献
Noguchi; Mochida; Shingu; et al.
Chemical and Pharmaceutical Bulletin, 1984 , vol. 32, # 9 p. 3584 - 3587
反应条件
1: 75 percent / ethyl acetate / 2 h 2: 280 mg / H2 / 1 percent PdCl2 / ethanol / 10 h 3: 10 percent NaOH / 4 h 4: 58 percent / pyridine / 1 h / 90 °C 5: 3 percent KOH / ethanol / 1 h / Heating View Scheme
参考文献
Noguchi; Mochida; Shingu; et al.
Chemical and Pharmaceutical Bulletin, 1984 , vol. 32, # 9 p. 3584 - 3587
反应条件
1: 66.7 percent / ammonia / methanol / 12 h 2: hydrogen / palladium on carbon / methanol; dimethylformamide View Scheme
参考文献
Proskuryakova; Bespalova; Pal'keeva; Petrichenko; Pankratova; Shokhonova; Anokhina
Russian Journal of Bioorganic Chemistry, 2005 , vol. 31, # 2 p. 119 - 127
反应条件
triethylamine in water; acetonitrile T=20°C; 1.66667 h;
参考文献
Gagnon, Paul; Huang, Xicai; Therrien, Eric; Keillor, Jeffrey W.
Tetrahedron Letters, 2002 , vol. 43, # 43 p. 7717 - 7719
反应条件
1: 1-hydroxybenzotriazole / acetonitrile 2: hydrogen / Pd/C / methanol / 2 h / cooling View Scheme
参考文献
Zvilichovsky, Gury; Gbara-Haj-Yahia, Isra
Journal of Organic Chemistry, 2004 , vol. 69, # 15 p. 4966 - 4973
反应条件
1: 81 percent / dimethylformamide / 20 h / 20 °C 2: H2 / Pd/C / methanol View Scheme
参考文献
Ovchinnikov, Mikhail V.; Bespalova, Zhanna D.; Molokoedov, Aleksandr S.; Revenko, Inna V.; Sepetov, Nikolai F.; et al
Collection of Czechoslovak Chemical Communications, 1989 , vol. 54, # 3 p. 772 - 783
反应条件
N,N'-Bis(2-oxo-3-oxazolidinyl)phosphorodiamidic azide; triethylamine in dichloromethane
参考文献
Katti, S. B.; Misra, P. K.; Haq, W.; Mathur, K. B.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. 27, # 1-12 p. 3 - 4
反应条件
4-(N,N-dimethlyamino)pyridine; triethylamine in acetonitrile
T=4°C; 0.833333 h;
参考文献
Pardin, Christophe; Gillet, Steve M.F.G.; Keillor, Jeffrey W.
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 24 p. 8379 - 8385
反应条件
sodium chloride; triethylamine in tetrahydrofuran
参考文献
Fujisawa Pharmaceutical Co., Ltd.
Patent: US3976635 A1, 1976 ;
反应条件
in ethanol; ethyl acetate
参考文献
Ajinomoto Co., Inc.
Patent: US3933783 A1, 1976 ;
