2-氯-3,5-二硝基吡啶合成路线 （共 24 条）
反应条件
N,N-dimethyl-formamide; trichlorophosphate T=90 - 100°C; 4 h;
参考文献
Rasheed, Khalid; Warkentin, James D.
Journal of Heterocyclic Chemistry, 1981 , vol. 18, p. 1581 - 1585
反应条件
1: nitric acid 2: phosphoryl chloride; phosphorus (V)-chloride View Scheme
参考文献
Journal of the Chemical Society, , p. 2590,2593
反应条件
1: nitric acid 2: phosphoryl chloride; phosphorus (V)-chloride View Scheme
参考文献
Journal of the Chemical Society, , p. 2590,2593
反应条件
hydrogen; palladium on activated carbon in ethanol T=25°C; P=2585.81 Torr; 18 h;
参考文献
AnorMED, Inc.
Patent: US6750348 B1, 2004 ;
Location in patent: Page column 113 ;
US 6750348 B1
反应条件
potassium permanganate; ammonia 1 h;
参考文献
Journal of Organic Chemistry, , vol. 50, # 4 p. 484 - 487
反应条件
ammonia T=-33°C; 1 h;
参考文献
Bie, Dick A. de; Geursten, Bart; Plas, Henk C. van der
Journal of Organic Chemistry, 1985 , vol. 50, # 4 p. 484 - 487
参考文献
State of Oregon, acting by and through The Oregon State Board of Higher Education, acting for and on behalf of The Oregon Health Sciences University and The University of Oregon, Eugene Oregon; The Regents of the University of California; ACEA Pharmaceuticals, Inc.
Patent: US5620978 A1, 1997 ;
US 5620978 A
反应条件
1: With hydrazine hydrate in dichloromethane T=20°C; 18 h; 2: With silver nitrate 3 h; Heating;
参考文献
Winkler, Michael; Cakir, Bayram; Sander, Wolfram
Journal of the American Chemical Society, 2004 , vol. 126, # 19 p. 6135 - 6149
反应条件
in methanol T=20°C; Substitution; KineticsActivation energy; Further Variations:TemperaturesReaction partners;
参考文献
El Hegazy, Fatma El-Zahraa M.; Abdel Fattah, Soheir Z.; Hamed, Ezzat A.; Sharaf, Saber M.
Journal of Physical Organic Chemistry, 2000 , vol. 13, # 9 p. 549 - 554
反应条件
1: ethanol 2: 1,4-diaza-bicyclo[2.2.2]octane / dimethyl sulfoxide / 25 °C View Scheme
参考文献
Asghar, Basim H.
Monatshefte fur Chemie, 2013 , vol. 144, # 3 p. 301 - 306
