(S)-(+)-1-苯基-1,2-乙二醇合成路线 （共 175 条）
反应条件
formic acid; triethylamine; [{(R,R)-TsNCHPhCHPhNHCH2(o-C6H4)C5Me4}RhCl] T=25°C; 5 h;
参考文献
Kanto Kagaku Kabushiki Kaisha
Patent: US2009/62573 A1, 2009 ;
Location in patent: Page/Page column 8; 11 ;
反应条件
lithium aluminium tetrahydride in ethylene glycol dimethyl ether T=0 - 20°C; Inert atmosphere;
参考文献
Alberti, Mariza N.; Vassilikogiannakis, Georgios; Orfanopoulos, Michael
Organic Letters, 2008 , vol. 10, # 18 p. 3997 - 4000
反应条件
(DHQ)2-PHAL; potassium carbonate; potassium hexacyanoferrate(III); osmium(VIII) oxide in water; tert-butyl alcohol T=0°C; Sharpless asymmetric dihydroxylation; 24 h;
参考文献
Pandey, Rajesh Kumar; Fernandes, Rodney A.; Kumar, Pradeep
Tetrahedron Letters, 2002 , vol. 43, # 25 p. 4425 - 4426
反应条件
Candida parapsilosis ATCC 7330 in ethanol; water T=25°C; 3 h; Enzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Mahajabeen, Pula; Chadha, Anju
Tetrahedron Asymmetry, 2011 , vol. 22, # 24 p. 2156 - 2160
反应条件
diisobutylaluminium hydride; (S)-1-methyl-2-lt;(piperidin-1-yl)-methylgt;pyrrolidine; tin(ll) chloride in dichloromethane T=-100°C; 0.333333 h; asymmetric reduction of prochiral hydroxy ketones; Product distribution;
参考文献
Chemistry Letters, , p. 1359 - 1362
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 8 h; Heating;
参考文献
Pandey, Ganesh; Gaikwad, Amrut L.; Gadre, Smita R.
Tetrahedron Letters, 2006 , vol. 47, # 5 p. 701 - 703
反应条件
[(R,R)-N,N'-bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminato(2-)]cobalt(III) acetate; water in tetrahydrofuran T=0 - 20°C; 48 h;
参考文献
Schaus, Scott E.; Brandes, Bridget D.; Larrow, Jay F.; Tokunaga, Makoto; Hansen, Karl B.; Gould, Alexandra E.; Furrow, Michael E.; Jacobsen, Eric N.
Journal of the American Chemical Society, 2002 , vol. 124, # 7 p. 1307 - 1315
反应条件
30 h; Candida parapsilosis IFO 0708, culture medium, glucose, pH 6.5;
参考文献
Hasegawa, Junzo; Ogura, Masahiro; Tsuda, Satoru; Maemoto, Shun-ichi; Kutsuki, Hidetoshi; Ohashi, Takehisa
Agricultural and Biological Chemistry, 1990 , vol. 54, # 7 p. 1819 - 1827
反应条件
potassium dioxotetrahydroxoosmate(VI); potassium carbonate; potassium hexacyanoferrate(III); methanesulfonamide; DHQD-PHAL-OPEG-OMe in water; tert-butyl alcohol T=0°C; 24 h; Title compound not separated from byproducts;
参考文献
Kuang, Yong-Qing; Zhang, Sheng-Yong; Wei, Ling-Ling
Tetrahedron Letters, 2001 , vol. 42, # 34 p. 5925 - 5927
反应条件
water T=37°C; rabbit liver microsomal epoxide hydrolase; Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 31, # 12 p. 828 - 831
