2,4,6-三甲基苯甲腈合成路线 （共 81 条）
反应条件
1: With 2,2,6,6-tetramethyl-1-piperidinyloxy, free radical; 1,3-Diiodo-5,5-dimethyl-2,4-imidazolidinedione in dichloromethane T=20°C; 0.5 h; Inert atmosphere; 2: With ammonia; iodine in dichloromethane; water T=20°C; 2 h; Inert atmosphere;
参考文献
Shimojo, Hiroyuki; Moriyama, Katsuhiko; Togo, Hideo
Synthesis (Germany), 2013 , vol. 45, # 15 art. no. SS-2013-F0311-OP, p. 2155 - 2164
反应条件
ammonia; iodine in water T=60°C; 4 h;
参考文献
Iida, Shinpei; Ohmura, Ryosuke; Togo, Hideo
Tetrahedron, 2009 , vol. 65, # 31 p. 6257 - 6262
反应条件
tris(dibenzylideneacetone)dipalladium(0) chloroform complex; 1,2-Ph2-3,4-bis(2,4,6-(t-Bu)3-phenylphophinidene)cyclobutene; zinc in various solvent(s) T=100°C; 16 h;
参考文献
Jensen, Rader S.; Gajare, Anil S.; Toyota, Kozo; Yoshifuji, Masaaki; Ozawa, Fumiyuki
Tetrahedron Letters, 2005 , vol. 46, # 50 p. 8645 - 8647
反应条件
[bis(acetoxy)iodo]benzene; ammonium hydrogen carbonate in methanol; water T=36°C; 12 h; Sealed tube;
参考文献
Xu, Jin-Hui; Jiang, Qing; Guo, Can-Cheng
Journal of Organic Chemistry, 2013 , vol. 78, # 23 p. 11881 - 11886
反应条件
[{Rh(OH)(cod)}2]; potassium carbonate in 1,4-dioxane T=80°C; 4 h; Inert atmosphere;
参考文献
Anbarasan, Pazhamalai; Neumann, Helfried; Beller, Matthias
Angewandte Chemie - International Edition, 2011 , vol. 50, # 2 p. 519 - 522
反应条件
1: 2-Bromo-1,3,5-trimethyl-benzene With magnesium; lithium chloride in tetrahydrofuran T=20°C; Inert atmosphere; 2: N-cyano-N-phenyl-p-methylbenzenesulfonamide in tetrahydrofuran T=0 - 20°C; Inert atmosphere;
参考文献
Anbarasan, Pazhamalai; Neumann, Helfried; Beller, Matthias
Chemistry - A European Journal, 2011 , vol. 17, # 15 p. 4217 - 4222
反应条件
ferrous acetate in 1,2-dichloro-ethane T=30°C; 6 h; Inert atmosphereSealed tube; regioselective reaction;
参考文献
Shu, Zhibin; Ji, Wenzhi; Wang, Xi; Zhou, Yujing; Zhang, Yan; Wang, Jianbo
Angewandte Chemie - International Edition, 2014 , vol. 53, # 8 p. 2186 - 2189
Angew. Chem., 2014 , vol. 53, # 8 p. 2218 - 2221,4
反应条件
Pb(II) thiocyanate T=200 - 230°C;
参考文献
Rudenko; Salfetnikova; Vasil'ev
Russian Journal of Organic Chemistry, 1996 , vol. 32, # 10 p. 1447 - 1470
反应条件
hydrogenchloride; aluminium trichloride in carbon disulfide T=0 - 5°C; 24 h;
参考文献
Buttke; Reiher; Niclas
Synthetic Communications, 1992 , vol. 22, # 15 p. 2237 - 2243
反应条件
palladium diacetate; triphenylphosphine in acetonitrile 1 h; Reflux;
参考文献
Kim, Hoo Sook; Kim, Sung Hwan; Kim, Jae Nyoung
Tetrahedron Letters, 2009 , vol. 50, # 15 p. 1717 - 1719
