3-(1H-咪唑-1-基)苯甲腈合成路线 (共 5 条)
反应条件
potassium carbonate in N,N-dimethyl-formamide T=100°C; 8 h;
参考文献
Bristol-Myers Squibb Pharma Company
Patent: EP946508 B1, 2009 ;
Location in patent: Page/Page column 34 ;
反应条件
copper(I) oxide; 4,7-Dimethoxy-1,10-phenanthroline; caesium carbonate; ethylene glycol; poly(ethylene glycol) in various solvent(s) T=90°C; 24 h;
参考文献
Altman, Ryan A.; Buchwald, Stephen L.
Organic Letters, 2006 , vol. 8, # 13 p. 2779 - 2782
反应条件
copper(l) iodide; potassium carbonate; heptakis(6-deoxy-6-amino)β-CD in dimethyl sulfoxide T=110°C; 18 h; Sealed tube;
参考文献
Suresh, Palaniswamy; Pitchumani, Kasi
Journal of Organic Chemistry, 2008 , vol. 73, # 22 p. 9121 - 9124
反应条件
potassium iodide; copper in ethanol; chloroform; water; N,N-dimethyl-formamide
参考文献
Sanofi
Patent: US5736548 A1, 1998 ;
反应条件
cesium fluoride in N,N-dimethyl-formamide T=60°C; 20 h; Inert atmosphere;
参考文献
Dehe, Daniel; Munstein, Isabel; Reis, Andreas; Thiel, Werner R.
Journal of Organic Chemistry, 2011 , vol. 76, # 4 p. 1151 - 1154