2-(4-溴苯基)-1-丙胺合成路线 (共 3 条)
反应条件
bromine; ZnBr2 on silica; hydrogen bromide in hexane; water
参考文献
ASTRAZENECA AB
Patent: WO2004/20415 A1, 2004 ;
Location in patent: Page 44 ;
WO 2004/020415 A1
反应条件
1: K2CO3 / 16 h / 180 °C 2: BH3*SMe2 / tetrahydrofuran / Heating View Scheme
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH
Patent: US2012/214785 A1, 2012 ;
反应条件
triethylamine in dichloromethane T=0 - 20°C;
参考文献
Ornstein; Zimmerman; Arnold; Bleisch; Cantrell; Simon; Zarrinmayeh; Baker; Gates; Tizzano; Bleakman; Mandelzys; Jarvie; Ho; Deverill; Kamboj
Journal of Medicinal Chemistry, 2000 , vol. 43, # 23 p. 4354 - 4358