(S)-(+)-1-茚醇合成路线 (共 57 条)
反应条件
2-acetyloxy-1-propene; lipase YS in di-isopropyl ether T=30°C; 7 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 10 p. 1253 - 1256
反应条件
lithium hydroxide in methanol 3 h; Heating;
参考文献
Tetrahedron, , vol. 58, # 20 p. 4085 - 4089
反应条件
NADH-H+; bovine liver catalase; P450cam in water; dimethyl sulfoxide T=25°C; pH=7.4; Product distributionEnzyme kineticsKinetics; Further Variations:Reagents;
参考文献
New Journal of Chemistry, , vol. 26, # 1 p. 35 - 42
反应条件
1: Candida antarctica B lipase; n-butanol / acetonitrile / 192 h 2: aq. LiOH / methanol / 3 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 58, # 20 p. 4085 - 4089
反应条件
potassium hydroxide in methanol
参考文献
Justus Liebigs Annalen der Chemie, , vol. 637, p. 57 - 72
反应条件
1: 90 percent / pyridine 2: 60 percent / LiAlH4 / tetrahydrofuran / Ambient temperature View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 11 p. 2767 - 2770
反应条件
1: pyridine 2: 75 percent / B2H6 / tetrahydrofuran 3: 90 percent / pyridine 4: 60 percent / LiAlH4 / tetrahydrofuran / Ambient temperature View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 11 p. 2767 - 2770
反应条件
1: 75 percent / B2H6 / tetrahydrofuran 2: 90 percent / pyridine 3: 60 percent / LiAlH4 / tetrahydrofuran / Ambient temperature View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 11 p. 2767 - 2770
反应条件
RuCl(η5-C9H7)(PPh3)2; Pseudomonas cepocia lipase; triethylamine T=60°C; Esterification; resolution of racemate; 43 h; Enzymatic reaction; Title compound not separated from byproducts;
参考文献
Tetrahedron Letters, , vol. 40, # 34 p. 6281 - 6284
反应条件
p-nitrobenzyl esterase from Bacillus subtilis in aq. phosphate buffer; ethanol 1 h; Enzymatic reaction;
参考文献
RSC Advances, , vol. 3, # 43 p. 20446 - 20449