2,2-二甲基-3-氧代-3-苯基丙酸乙酯合成路线 （共 31 条）
反应条件
oxalyl dichloride; dimethyl sulfoxide; triethylamine in dichloromethane T=-60°C; 0.333333 h;
参考文献
Smith, Amos B.; Levenberg, Patricia A.
Synthesis, 1981 , # 7 p. 567 - 570
反应条件
1: 2-dimethylstibanyl-2-methylpropionic acid ethyl ester With Me4ZnLi2 in tetrahydrofuran T=-78°C; 0.5 h; 2: benzoyl chloride in tetrahydrofuran T=-78 - 20°C; 1 h;
参考文献
Kayahara, Eiichi; Yamada, Hiroto; Yamago, Shigeru
Chemistry - A European Journal, 2011 , vol. 17, # 19 p. 5272 - 5280
反应条件
lithium hydroxide 1.) THF, 55 deg C, 15 min, 2.) THF, 24 h; Yield given. Multistep reaction;
参考文献
Ohkuma, Takeshi; Sandoval, Christian A.; Srinivasan, Rajagopal; Lin, Quinghong; Wei, Yinmao; Muniz, Kilian; Noyori, Ryoji
Journal of the American Chemical Society, 2005 , vol. 127, # 23 p. 8288 - 8289
反应条件
diethyl ether; triphenylmethyl-sodium anschliessend Behandeln mit Benzoylchlorid;
参考文献
Thompson et al.
Journal of Organic Chemistry, 1954 , vol. 19, p. 1490,1491, 1496
反应条件
lithium salts of diamines T=-78°C;
参考文献
Lai, John T.
Journal of Organic Chemistry, 1985 , vol. 50, # 8 p. 1329 - 1330
反应条件
toluene; zinc; benzene T=150°C;
参考文献
Bloom; Hauser
Journal of the American Chemical Society, 1944 , vol. 66, p. 153
反应条件
sodium hydride; benzene
参考文献
Lewis, Frederick D.; Bassani, Dario M.; Reddy, G. Dasharatha
Journal of Organic Chemistry, 1993 , vol. 58, # 23 p. 6390 - 6393
反应条件
methanol; titanium tetrachloride in dichloromethane Ambient temperatureaddition of reagents at -78 deg C, 2 h; reaction at room temperature;
参考文献
Reddy, Chaganti P.; Tanimoto, Shigeo
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 411 - 414
反应条件
toluene; zinc; benzene
参考文献
Bayless; Hauser
Journal of the American Chemical Society, 1954 , vol. 76, p. 2306
反应条件
1: Diisopropylamine, butyllithium / THF, -78 deg C; 1.) 50 min, 2.) 5 min 2: 84 percent / 1. DMSO/oxalyl chloride; 2.(C2H5)3N / CH2Cl2 / 0.33 h / -60 °C View Scheme
参考文献
Smith, Amos B.; Levenberg, Patricia A.
Synthesis, 1981 , # 7 p. 567 - 570
