四氢-6-(2-戊炔基)-2H-吡喃-2-酮合成路线 （共 12 条）
反应条件
toluene-4-sulfonic acid in benzene
Heating; Yield given;
参考文献
Utaka, Masanori; Kuriki, Hidesuke; Sakai, Takashi; Takeda, Akira
Chemistry Letters, 1983 , p. 911 - 912
反应条件
1: 1.) LDA / 1.) THF, hexane, -10 deg C, 15 min, 2.) THF, hexane, -50 deg C, 6 h
2: Al2O3 / diethyl ether / 6 h / Ambient temperature
3: 99 percent / O2, methylene blue / methanol / 3 h / 0 °C / Irradiation
4: NaBH4, NaHCO3 / H2O / 2 h / Ambient temperature
5: p-TsOH / benzene / Heating
View Scheme
参考文献
Utaka, Masanori; Kuriki, Hidesuke; Sakai, Takashi; Takeda, Akira
Journal of Organic Chemistry, 1986 , vol. 51, # 6 p. 935 - 938
反应条件
1: NaBH4, NaHCO3 / H2O / 2 h / Ambient temperature
2: p-TsOH / benzene / Heating
View Scheme
参考文献
Utaka, Masanori; Kuriki, Hidesuke; Sakai, Takashi; Takeda, Akira
Journal of Organic Chemistry, 1986 , vol. 51, # 6 p. 935 - 938
反应条件
1: 99 percent / O2, methylene blue / methanol / 3 h / 0 °C / Irradiation
2: NaBH4, NaHCO3 / H2O / 2 h / Ambient temperature
3: p-TsOH / benzene / Heating
View Scheme
参考文献
Utaka, Masanori; Kuriki, Hidesuke; Sakai, Takashi; Takeda, Akira
Journal of Organic Chemistry, 1986 , vol. 51, # 6 p. 935 - 938
反应条件
1: Al2O3 / diethyl ether / 6 h / Ambient temperature
2: 99 percent / O2, methylene blue / methanol / 3 h / 0 °C / Irradiation
3: NaBH4, NaHCO3 / H2O / 2 h / Ambient temperature
4: p-TsOH / benzene / Heating
View Scheme
参考文献
Utaka, Masanori; Kuriki, Hidesuke; Sakai, Takashi; Takeda, Akira
Journal of Organic Chemistry, 1986 , vol. 51, # 6 p. 935 - 938
反应条件
1: 1.) LDA / 1.) THF, hexane, -10 deg C, 15 min, 2.) THF, hexane, -50 deg C, 6 h
2: Al2O3 / diethyl ether / 6 h / Ambient temperature
3: 99 percent / O2, methylene blue / methanol / 3 h / 0 °C / Irradiation
4: NaBH4, NaHCO3 / H2O / 2 h / Ambient temperature
5: p-TsOH / benzene / Heating
View Scheme
参考文献
Utaka, Masanori; Kuriki, Hidesuke; Sakai, Takashi; Takeda, Akira
Journal of Organic Chemistry, 1986 , vol. 51, # 6 p. 935 - 938
反应条件
1: 1.) zinc chips / 1.) THF, 0 deg C, 1 h, 2.) THF, 25 deg C, 1h
2: dimethylsulfoxide / 200 °C
3: 71 percent / lithium amide / liquid ammonia; tetrahydrofuran / 0.75 h
4: 1.) 35percent H2O2, conc. H2SO4, 2.) triethylamine, acetic anhydride / 1.) THF, 20 deg C, 24 h, 2.) 20 deg C, 2 h
View Scheme
参考文献
Fehr, Charles; Galindo, Jose; Ohloff, Guenther
Helvetica Chimica Acta, 1981 , vol. 64, # 5 p. 1247 - 1256
反应条件
1: 71 percent / lithium amide / liquid ammonia; tetrahydrofuran / 0.75 h
2: 1.) 35percent H2O2, conc. H2SO4, 2.) triethylamine, acetic anhydride / 1.) THF, 20 deg C, 24 h, 2.) 20 deg C, 2 h
View Scheme
参考文献
Fehr, Charles; Galindo, Jose; Ohloff, Guenther
Helvetica Chimica Acta, 1981 , vol. 64, # 5 p. 1247 - 1256
反应条件
1: dimethylsulfoxide / 200 °C
2: 71 percent / lithium amide / liquid ammonia; tetrahydrofuran / 0.75 h
3: 1.) 35percent H2O2, conc. H2SO4, 2.) triethylamine, acetic anhydride / 1.) THF, 20 deg C, 24 h, 2.) 20 deg C, 2 h
View Scheme
参考文献
Fehr, Charles; Galindo, Jose; Ohloff, Guenther
Helvetica Chimica Acta, 1981 , vol. 64, # 5 p. 1247 - 1256
反应条件
1: 1) diisopropylamine, n-BuLi / 1) THF, -10 deg C, 30 min; 2) THF, -50 deg C
2: Al2O3 / diethyl ether / 6 h / Ambient temperature
3: 100 percent / O2, methylene blue / methanol / 3 h / 5 °C / Irradiation
4: NaBH4, NaHCO3 / H2O
5: TsOH / benzene / Heating
View Scheme
参考文献
Utaka, Masanori; Kuriki, Hidesuke; Sakai, Takashi; Takeda, Akira
Chemistry Letters, 1983 , p. 911 - 912
