S-(4-甲氧基苄基)-L-半胱氨酸合成路线 （共 16 条）
反应条件
trifluoroacetic acid in dichloromethane 1.) 0 deg C, 1 h; 2.) RT, 30 min;
参考文献
Richter, Lutz S.; Marsters Jr., James C.; Gadek, Thomas R.
Tetrahedron Letters, 1994 , vol. 35, # 11 p. 1631 - 1634
反应条件
1: (4-methoxyphenyl)methanol With hydrogenchloride in diethyl ether; water 3 h; 2: (R)-cysteine With sodium hydroxide in diethyl ether; ethanol; water T=20°C; 2 h; 3: With hydrogenchloride in diethyl ether; ethanol; water T=0°C; pH=7;
参考文献
LG Life Sciences Ltd.
Patent: US2010/267708 A1, 2010 ;
Location in patent: Page/Page column 23-24 ;
反应条件
methanesulfonic acid; 3-methyl-phenol in dichloromethane T=25°C; 0.5 h;
参考文献
Tamamura; Nakamura; Noguchi; Funakoshi; Fujii
Chemical and Pharmaceutical Bulletin, 1993 , vol. 41, # 5 p. 954 - 957
反应条件
sodium hydroxide in ethanol; chloroform; water T=20°C;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 19, # 2 p. 442 - 446
反应条件
triethylsilane; trifluoroacetic acid in dichloromethane Ambient temperature;
参考文献
Tetrahedron Letters, , vol. 35, # 11 p. 1631 - 1634
反应条件
1: CF3CO2H / diethyl ether 2: HF View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 27, # 9 p. 2151 - 2156
反应条件
trifluoroacetic acid
参考文献
Journal of Organic Chemistry, , vol. 41, # 8 p. 1336 - 1340
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 27, # 9 p. 2151 - 2156
反应条件
trimethylsilyl trifluoromethanesulfonate; methyl-phenyl-thioether in trifluoroacetic acid T=0°C; 0.5 h; New peptide deprotection procedure: hard-soft acid-base concept; the role of soft bases (thioanisole, dimethylsulfide, diphenylsulfide) employed.; Product distribution;
参考文献
Fujii; Otaka; Ikemura; Hatano; Okamachi; Funakoshi; Sakurai; Shioiri; Yajima
Chemical and pharmaceutical bulletin, 1987 , vol. 35, # 8 p. 3447 - 3452
反应条件
dimethylsulfide; trifluorormethanesulfonic acid in trifluoroacetic acid T=0°C; 1 h;
参考文献
Fujii, Nobutaka; Otaka, Akira; Watanabe, Toshihiro; Arai, Hiromitsu; Funakoshi, Susumu; et al.
Journal of the Chemical Society, Chemical Communications, 1987 , p. 1676 - 1678
