N,N-二甲基-5-(苄氧基)-1H-吲哚-3-乙胺合成路线 （共 8 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran; diethyl ether 6 h; Heating;
参考文献
Barf; De Boer; Wikstrom; Peroutka; Svensson; Ennis; Ghazal; McGuire; Smith
Journal of Medicinal Chemistry, 1996 , vol. 39, # 24 p. 4717 - 4726
参考文献
Merck Sharp and Dohme Ltd.
Patent: US6187805 B1, 2001 ;
US 6187805 B1
反应条件
sodium methylate; sodium cyanoborohydride; acetic acid in methanol; water T=20°C; 4 h;
参考文献
Russell; Baker; Barden; Beer; Bristow; Broughton; Knowles; McAllister; Patel; Castro
Journal of Medicinal Chemistry, 2001 , vol. 44, # 23 p. 3881 - 3895
反应条件
1: benzene 2: LiAlH4; THF View Scheme
参考文献
Kondo et al.
Itsuu Kenkyusho Nempo, 1959 , # 10 p. 1,6; engl. Ref. S. 33, 40
Chem.Abstr., 1960 , p. 492
反应条件
1: Ba 2810 With vinylsulfonylmethyl polystyrene in N,N-dimethyl-formamide 2: methyl iodide in N,N-dimethyl-formamide 3: With N-ethyl-N,N-diisopropylamine in dichloromethane Hoffman elimination; Further stages.;
参考文献
Wu, Tom Y. H.; Schulte, Peter G.
Organic Letters, 2002 , vol. 4, # 23 p. 4033 - 4035
反应条件
tetrahydrofuran; lithium aluminium tetrahydride
参考文献
Stoll et al.
Helvetica Chimica Acta, 1955 , vol. 38, p. 1452,1469
Full Text Show Details
Upjohn Co.
Patent: US2804462 , 1952 ;
反应条件
palladium on activated charcoal; ethanol Hydrogenation;
参考文献
Kondo et al.
Itsuu Kenkyusho Nempo, 1959 , # 10 p. 1,6; engl. Ref. S. 33, 40
Chem.Abstr., 1960 , p. 492
反应条件
1: palladium/BaSO4; methanol
2: methanol
View Scheme
参考文献
Kondo et al.
Itsuu Kenkyusho Nempo, 1959 , # 10 p. 1,6; engl. Ref. S. 33, 40
Chem.Abstr., 1960 , p. 492
